Evidence map›Paper›PMID 40833252›Full record

ArticleeLife2025

Inhibitory basal ganglia nuclei differentially innervate pedunculopontine nucleus subpopulations and evoke differential motor and valence behaviors.

Michel Fallah, Kenea C Udobi, Aleksandra E Swiatek, Chelsea B Scott, Rebekah C Evans

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Cognitive functions of the GPe.Trends in neurosciences · 2026
    Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Michel FallahInterdisciplinary Program in Neuroscience, Georgetown University, Washington DC, United States.ORCID https://orcid.org/0000-0001-9762-4087
Kenea C UdobiDepartment of Neuroscience, Georgetown University Medical Center, Washington DC, United States.
Aleksandra E SwiatekDepartment of Neuroscience, Georgetown University Medical Center, Washington DC, United States.
Chelsea B ScottDepartment of Neuroscience, Georgetown University Medical Center, Washington DC, United States.
Rebekah C EvansInterdisciplinary Program in Neuroscience, Georgetown University, Washington DC, United States.ORCID https://orcid.org/0000-0002-9476-150X

Funding

Tissue Culture Shared ResourceP30CA051008 · NCI · GEORGETOWN UNIVERSITY · PI MARCUS S NOEL · 1990 to 2026
$71.5M
Dissecting the inhibitory architecture governing basal ganglia outputR00NS112417 · NINDS · GEORGETOWN UNIVERSITY · PI EVANS, REBEKAH COLEMAN · 2021 to 2023
$806k
Upgrade Existing Multiwell, Fluorescence Timelapse Imaging Workstation to ConfocaS10RR025661 · NCRR · GEORGETOWN UNIVERSITY · PI MUELLER, SUSETTE C · 2009 to 2009
$237k
Dissecting functional subgroups and closed-loop circuits between the pedunculopontine nucleus and the basal gangliaF30NS132399 · NINDS · GEORGETOWN UNIVERSITY · PI Michel Fallah · 2023 to 2026
$181k
BRAIN Initiative R00NS112417Michael J Fox Foundation for Parkinson's Research MJFF-022863NCI NIH HHS P30 CA051008NCRR NIH HHS S10 RR025661NINDS NIH HHS F30 NS132399NINDS NIH HHS F30NS132399NINDS NIH HHS R00 NS112417Parkinson's Foundation PF-SSF-941810
6 · The paper itself

Abstract

The canonical basal ganglia model predicts that the substantia nigra

Indexed as

Basal GangliaLocomotionPedunculopontine Tegmental NucleusAnimalsBehavior, AnimalGABAergic NeuronsGlobus PallidusMaleMiceOptogeneticsbrainstemdopamineGABAinhibitionlocomotionmouseneurosciencevalence

Identifiers

PMID40833252
PMCPMC12367300

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.