Evidence map›Paper›PMID 40833190›Full record

ArticleThe Laryngoscope2026

Management of Subglottic Stenosis With the "Maddern Procedure": Long Term Follow-Up Outcomes.

Emilie A C Dronkers, Gemma M Clunie, Aphrodite Iacovidou, S A Reza Nouraei, Chadwan Al Yaghchi, Guri S Sandhu

Abstract read
In one paragraph

Article in The Laryngoscope, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Speech and language therapy management of laryngotracheal stenosis - what has changed.Current opinion in otolaryngology & head and neck surgery · 2026
    Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Emilie A C DronkersNational Centre for Airway Reconstruction, Imperial College Healthcare NHS Trust, London, UK.ORCID 0009-0004-8156-2589
Gemma M ClunieNational Centre for Airway Reconstruction, Imperial College Healthcare NHS Trust, London, UK.
Aphrodite IacovidouNational Centre for Airway Reconstruction, Imperial College Healthcare NHS Trust, London, UK.
S A Reza NouraeiDepartment of Otolaryngology, Nottingham University Hospitals NHS Trust, Nottingham, UK.ORCID 0000-0002-5604-1739
Chadwan Al YaghchiNational Centre for Airway Reconstruction, Imperial College Healthcare NHS Trust, London, UK.
Guri S SandhuNational Centre for Airway Reconstruction, Imperial College Healthcare NHS Trust, London, UK.

Funding

NIHR Imperial Biomedical Research Centre (BRC)
6 · The paper itself

Abstract

objectiveFull-thickness resection and skin grafting of the laryngotracheal junction, the "Maddern Procedure," can be used to treat patients with recalcitrant laryngotracheal stenosis. We report the long-term surgical outcomes of this procedure.

methodsA consecutive series of 27 females with idiopathic, iatrogenic, or vasculitic subglottic stenosis who underwent the Maddern procedure between 2012 and 2023 were retrospectively reviewed. Airway outcome was assessed using the Modified Medical Research Council Dyspnea (mMRC) Scale. Secondary outcomes included voice, swallowing, mucus management, complications, and the need for subsequent airway surgery.

resultsMost patients had idiopathic subglottic stenosis (n = 20, 74.1%), followed by vasculitic (n = 4, 14.8%) and intubation-related (n = 3, 11.1%) etiologies. Patients had an average of 7.3 (SD 3.4) endoscopic procedures before undergoing the Maddern procedure. Mean pre-Maddern inter-treatment interval was 7.5 months (SD 3.4). The median follow-up was 6.6 years (interquartile range 0.75-11.3). The mMRC dyspnea scale improved from 2.7 (SD 0.73) to 0.52 (SD 0.85). The five-year recurrence-free rate was 63%. It differed between etiologies, ranging from 83% for idiopathic stenosis to 67% for intubation-related and 0% for vasculitis-related stenoses. During the first 4 years after Maddern, 67% of patients reported daily cough and the need to use nebulizers regularly.

conclusionThe Maddern procedure is an effective and durable option for patients with idiopathic subglottic stenosis. Careful screening of patients with presumed idiopathic subglottic stenosis for possible underlying auto-immune conditions remains important when considering patients for this procedure. LEVEL OF EVIDENCE: Level 4.

Indexed as

LaryngostenosisTracheal StenosisAdultAgedFemaleFollow-Up StudiesHumansMiddle AgedRetrospective StudiesTreatment Outcomeairway reconstructionairway stenosis—clinicalairway stenosis/reconstructionotolaryngologyotorhinolaryngology

Identifiers

PMID40833190
PMCPMC13001711

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.