Evidence map›Paper›PMID 40833127›Full record

ArticleJournal of clinical microbiology2025

Luciferase reporter mycobacteriophage (TM4::

Saranathan Rajagopalan, Lahari Das, Donna J Kohlerschmidt, Amy K Rourke, Salika M Shakir, Michelle H Larsen, Max R O'Donnell, Wendy A Szymczak, Vincent E Escuyer, Phyu M Thwe and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical microbiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Saranathan RajagopalanDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York, USA.ORCID 0000-0003-2201-8028
Lahari DasDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York, USA.
Donna J KohlerschmidtNew York State Department of Health, Wadsworth Center, Albany, New York, USA.
Amy K RourkeNew York State Department of Health, Wadsworth Center, Albany, New York, USA.
Salika M ShakirDepartment of Pathology, The University of Utah School of Medicine, Salt Lake City, Utah, USA.
Michelle H LarsenDepartment of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York, USA.
Max R O'DonnellDivision of Pulmonary, Allergy, and Critical Care Medicine, Columbia University Medical Center, New York, New York, USA.
Wendy A SzymczakDepartment of Pathology, Montefiore Medical Center, New York, New York, USA.ORCID 0000-0002-0747-1169
Vincent E EscuyerNew York State Department of Health, Wadsworth Center, Albany, New York, USA.
Phyu M Thwe *Department of Pathology, Montefiore Medical Center, New York, New York, USA.ORCID 0000-0003-3250-9998
William R Jacobs *Department of Microbiology and Immunology, Albert Einstein College of Medicine, New York, New York, USA.ORCID 0000-0003-3321-3080

Funding

Einstein-Montefiore Clinical and Translational Science Award HubUM1TR004400 · NCATS · ALBERT EINSTEIN COLLEGE OF MEDICINE · PI Jessica Kahn, Mimi Y Kim · 2023 to 2026
$17.3M
Novel Reporter Phages to Detect Complex TB Drug Resistance and PersistenceR01AI114900 · NIAID · ALBERT EINSTEIN COLLEGE OF MEDICINE, INC · PI Michelle H Larsen, Max O'Donnell · 2015 to 2026
$7.2M
MOLECULAR GENETIC ANALYSIS OF MYCOBACTERIUM TUBERCULOSISR01AI026170 · NIAID · YESHIVA UNIVERSITY · PI JACOBS, WILLIAM ROBERT · 1989 to 2022
$7.1M
Rapid phenotypic detection of complex and emergent TB drug-resistance using a next-generation nanoluciferase reporter phageR01AI176407 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Max O'Donnell · 2023 to 2026
$3.0M
Targeted next-generation sequencing to enhance detection and genomic characterization of Mycobacterium tuberculosis and high-impact bacterial pathogens among HIV-infected adults with sepsis in UgandaR21AI143417 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI O'DONNELL, MAX · 2020 to 2021
$468k
Nanoluciferase reporter phage for rapid phenotypic characterization of resistance to next-generation antimycobacterial agentsR21AI168940 · NIAID · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI JACOBS, WILLIAM ROBERT, O'DONNELL, MAX · 2023 to 2024
$421k
Albert Einstein College of Medicine, Yeshiva University G12294CTSA UM1TR004400NCATS NIH HHS UM1 TR004400NIAID NIH HHS R01 AI026170NIAID NIH HHS R01 AI114900NIAID NIH HHS R01 AI176407NIAID NIH HHS R21 AI143417NIAID NIH HHS R21 AI168940NIH HHS R01-AI026170NIH HHS R01-AI114900NIH HHS R01-AI176407NIH HHS R21-AI168940
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Anti-Bacterial AgentsDrug Resistance, BacterialLuciferasesMacrolidesMycobacteriophagesMycobacterium abscessusAmikacinClarithromycinGenes, ReporterHumansMicrobial Sensitivity TestsMycobacterium Infections, NontuberculousAmikacinAnti-Bacterial AgentsClarithromycinLuciferasesMacrolidesamikacinerm(41)inducible macrolide resistanceluciferase reporter mycobacteriophageMycobacterium abscessus

Identifiers

PMID40833127
PMCPMC12421814

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.