ArticleMicrobiology spectrum2025
From microscopy to molecular diagnostics: identifying the complexities of clinical diagnostics for vaginal infections.
Article in Microbiology spectrum, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Therapeutic Tools for Vulvovaginal Candidiasis: Current and Emerging Antifungal Agents.Journal of fungi (Basel, Switzerland) · 2026Review
- Volatile organic compound profiling by HS-GC-IMS for vaginal infection identification.Frontiers in cellular and infection microbiology · 2026Article
- Perspectives on Vaginal Ecology and Management of Recurrent Vulvovaginal Candidiasis: A Narrative Review.Journal of fungi (Basel, Switzerland) · 2025Review
Corrections and comments
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Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of molecular-based assays to diagnose vaginitis has become increasingly common. In a recent study, J. Elvy, K. Carter, J. Paterson, M. Smith, et al. (Microbiol Spectr 13: e0127424, 2025, https://doi.org/10.1128/spectrum.01274-24) compared the performance of the Hologic Panther Aptima BV and CV/TV assays for the diagnosis of vaginitis to that of the current standard-of-care diagnostic methods that include microscopy, culture, and PCR. The study suggests that the Hologic Panther Aptima BV and CV/TV assays are useful alternatives to conventional testing but would likely lead to higher treatment rates and additional testing costs. However, additional studies are needed to determine the clinical significance of these diagnostic assays, especially for BV and vulvovaginal candidiasis, wherein the presence or absence of specific organisms does not necessarily indicate clinical disease.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.