Evidence map›Paper›PMID 40832807›Full record

ArticleJournal of biological rhythms2025

It's Not Just Light: Assessing the Intrinsic Period of the Human Circadian Pacemaker Under Dim Light Conditions Should Include Non-Photic Influences.

Melissa A St Hilaire, Charles A Czeisler, Elizabeth B Klerman

Abstract readLetter
In one paragraph

Article in Journal of biological rhythms, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Melissa A St HilaireDepartment of Computer and Data Sciences, School of Engineering and Computational Sciences, Merrimack College, North Andover, Massachusetts.ORCID 0000-0002-5700-8391
Charles A CzeislerDivision of Sleep Medicine, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-7408-1849
Elizabeth B KlermanDivision of Sleep Medicine, Harvard Medical School, Boston, Massachusetts.ORCID 0000-0002-7402-3171

Funding

Determining The Role of Photic and Non-Photic Time Cues in Resetting Lipid Circadian Rhythms in HumansR01HL159207 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI RAHMAN, SHADAB A · 2021 to 2024
$3.5M
Proteomic and Transcriptomic Biomarkers of Circadian TimingR01HL148704 · NHLBI · STANFORD UNIVERSITY · PI DUFFY, JEANNE F, MIGNOT, EMMANUEL J · 2020 to 2023
$3.4M
Influence of Nocturnal Light Exposure on the Impairment of Glucose Tolerance Induced by Chronic Sleep RestrictionR01DK127254 · NIDDK · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A · 2021 to 2024
$3.1M
Testing Effects of Melatonin on Uterine Contractions in WomenR01HD107064 · NICHD · MASSACHUSETTS GENERAL HOSPITAL · PI KLERMAN, ELIZABETH B. · 2022 to 2025
$3.0M
Impact of sex and age on non-visual light input that affects sleep and circadian rhythmsR01HL166205 · NHLBI · MASSACHUSETTS GENERAL HOSPITAL · PI KLERMAN, ELIZABETH B. · 2023 to 2025
$1.6M
Real-time breath metabolomics: A new direction for circadian biomarkersR21HL161464 · NHLBI · BRIGHAM AND WOMEN'S HOSPITAL · PI CZEISLER, CHARLES A · 2022 to 2023
$492k
NHLBI NIH HHS R01 HL148704NHLBI NIH HHS R01 HL159207NHLBI NIH HHS R01 HL166205NHLBI NIH HHS R21 HL161464NICHD NIH HHS R01 HD107064NIDDK NIH HHS R01 DK127254
6 · The paper itself

Abstract

Response to: "Mathematical Analysis of Light-sensitivity Related Challenges in Assessment of the Intrinsic Period of the Human Circadian Pacemaker".

Indexed as

Biological ClocksCircadian ClocksCircadian RhythmLightHumansblind individualsdim lightforced desynchronyintrinsic periodmathematical modelsvelocity response curve

Identifiers

PMID40832807
PMCPMC13043181

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.