ReviewMovement disorders clinical practice2026
The Management of Parkinson's Disease Before, during and after Pregnancy-an MDS Scientific Issues Committee Review.
Review in Movement disorders clinical practice, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- About pregnancy in Parkinson's disease.Journal of Parkinson's disease · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundPregnancy after a Parkinson's diagnosis presents complex challenges. Due to the paucity of literature, there is no evidence-based guidelines and protocols for preconception care, management of pregnancy, childbirth and the postpartum period in women with early-onset Parkinson's disease (PD). Decision-making can be fraught with uncertainty for both patients and healthcare providers.
objectivesThis review is aimed to provide pragmatic advice to help guide women with PD before, during and after pregnancy, and to address key gaps in the existing literature.
methodsAn interdisciplinary working group of movement disorder specialists, obstetricians, perinatal neuropsychiatrists, physiotherapist, pharmacist and individuals with lived experiences collaborated to assess published evidence. In areas lacking robust data, recommendations were derived from case studies, registries, clinical and personal expertise.
resultsKey recommendations include: Motor Symptom Management: Levodopa remains the safest treatment during the perinatal period. Monotherapy is preferred over polypharmacy. Non-Motor Symptom Management: Some non-motor symptoms are particularly common in this patient group and warrant individualized care. Preconception Considerations: Proactive planning about medical management should be done before conception. Genetic counseling and screening should be provided if desired. Peripartum and Postpartum Considerations: The decision regarding mode of delivery should be based upon women's birth plans and obstetric indications. Breastfeeding should be cautiously considered depending on the need for pharmacological treatment.
conclusionsThis article provides a framework for managing PD before, during and after pregnancy. Collaborative efforts and ongoing registries like PregSpark* will be important to develop robust, evidence-based guidelines in this unique population.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.