Evidence map›Paper›PMID 40832631›Full record

ArticleMolecular therapy. Nucleic acids2025

mRNA-LNP vaccine encoding the

Amporn Limsalakpetch, Utaiwan Kum-Arb, Kosol Yongvanitchit, Rawiwan Im-Erbsin, Ratawan Ubalee, Norman Waters, Brian A Vesely, Hiromi Muramatsu, Drew Weissman, Ying K Tam and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular therapy. Nucleic acids, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. An mRNA-lipid nanoparticle vaccine targeting theMolecular therapy. Nucleic acids · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Amporn LimsalakpetchDepartment of Bacterial and Parasitic Diseases, WRAIR-AFRIMS, Bangkok 10400, Thailand.
Utaiwan Kum-ArbDepartment of Bacterial and Parasitic Diseases, WRAIR-AFRIMS, Bangkok 10400, Thailand.
Kosol YongvanitchitDepartment of Bacterial and Parasitic Diseases, WRAIR-AFRIMS, Bangkok 10400, Thailand.
Rawiwan Im-ErbsinDepartment of Bacterial and Parasitic Diseases, WRAIR-AFRIMS, Bangkok 10400, Thailand.
Ratawan UbaleeDepartment of Bacterial and Parasitic Diseases, WRAIR-AFRIMS, Bangkok 10400, Thailand.
Norman WatersDepartment of Bacterial and Parasitic Diseases, WRAIR-AFRIMS, Bangkok 10400, Thailand.
Brian A VeselyDepartment of Bacterial and Parasitic Diseases, WRAIR-AFRIMS, Bangkok 10400, Thailand.
Hiromi MuramatsuDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Drew WeissmanDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Ying K TamAcuitas Therapeutics, Vancouver, BC V6T 1Z3, Canada.
Shigeto YoshidaLaboratory of Vaccinology and Applied Immunology, School of Pharmacy, Kanazawa University, Kanazawa, Ishikawa 920-1192, Japan.
John AdamsCenter for Global Health and Infectious Diseases Research and USF Genomics Program, College of Public Health, University of South Florida, Tampa, FL 33612, USA.
Anjali YadavaBiologics Research & Development Branch, CIDR, Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA.
Norbert PardiDepartment of Microbiology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Sathit PichyangkulDepartment of Bacterial and Parasitic Diseases, WRAIR-AFRIMS, Bangkok 10400, Thailand.

Funding

Accelerating discovery of an efficacious Plasmodium vivax multivalent multi-stage vaccineU01AI155361 · NIAID · UNIVERSITY OF SOUTH FLORIDA · PI ADAMS, JOHN H · 2021 to 2025
$4.8M
NIAID NIH HHS U01 AI155361
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

circumsporozoite proteinlipid nanoparticlemRNA vaccineMT: Oligonucleotides: Therapies and Applicationsnucleoside-modificationP. vivaxtransgenic sporozoite challenge mouse model

Identifiers

PMID40832631
PMCPMC12359152

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.