ArticleNuclear engineering and technology2025
Korean-specific internal dosimetry data for radioiodine bioassay and evaluation of the dosimetric impact.
Article in Nuclear engineering and technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Our earlier works focused on exploring the Korean iodine biokinetic model and calculating Korean-specific S values and dose coefficients. Building on this foundation, this study extended our efforts to establish an extensive dosimetry dataset for Korean-specific iodine bioassay. We calculated bioassay functions (e.g., thyroid retention and urinary excretion functions), dose-per-content-functions, and content for the specified doses based on the Korean biokinetic model and dose coefficients previously developed. Also, this study provides a comprehensive understanding of the practical impact of using Korean-specific dosimetry data. Compared to the ICRP reference data, the thyroid retention functions for Koreans were significantly lower (for I-131, peaks at 18% vs. 27%). The physical half-lives of radioiodine played a significant role in the differences of dose-per-content-function. For long-lived iodine isotopes such as I-125, the dose-per-content-functions were comparable to ICRP data, whereas for short-lived iodine isotopes such as I-131, the higher values were observed in the Korean data, indicating a greater dose estimation for a given iodine activity measured in the thyroid. Although we revealed the differences between Korean and ICRP reference data, the comprehensive understanding of Korean data suggests that using the Korean-specific data should be considered only when high doses are predicted.
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