Evidence map›Paper›PMID 40832413›Full record

ArticlemedRxiv : the preprint server for health sciences2025

Scoring Physician Risk Communication in Prostate Cancer Using Large Language Models.

Guillermo Lopez-Garcia, Dongfang Xu, Michael Luu, Renning Zheng, Timothy J Daskivich, Graciela Gonzalez-Hernandez

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors.

Guillermo Lopez-GarciaDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0001-5903-1483
Dongfang XuDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.ORCID 0000-0003-0828-1102
Michael LuuDepartment of Biostatistics, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Renning ZhengDepartment of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Timothy J DaskivichDepartment of Urology, Cedars-Sinai Medical Center, Los Angeles, CA, USA.
Graciela Gonzalez-HernandezDepartment of Computational Biomedicine, Cedars-Sinai Medical Center, Los Angeles, CA, USA.

Funding

Natural Language Processing Based Consultation Feedback to Improve Patient Decision Making and Physician Risk CommunicationR01CA290559 · NCI · CEDARS-SINAI MEDICAL CENTER · PI TIMOTHY DASKIVICH · 2025 to 2026
$761k
NCI NIH HHS R01 CA290559
6 · The paper itself

Abstract

Effective risk communication is essential to shared decision-making in prostate cancer care. However, the quality of physician communication of key tradeoffs varies widely in real-world consultations. Manual evaluation of communication is labor-intensive and not scalable. We present a structured, rubric-based framework that uses large language models (LLMs) to automatically score the quality of risk communication in prostate cancer consultations. Using transcripts from 20 clinical visits, we curated and annotated 487 physician-spoken sentences that referenced five decision-making domains: cancer prognosis, life expectancy, and three treatment side effects (erectile dysfunction, incontinence, and irritative urinary symptoms). Each sentence was assigned a score from 0 to 5 based on the precision and patient-specificity of communicated risk, using a validated scoring rubric. We modeled this task as five multiclass classification problems and evaluated both fine-tuned transformer baselines and GPT-4o with rubric-based and chain-of-thought (CoT) prompting. Our best performing approach, which combined rubric-based CoT prompting with few-shot learning, achieved micro averaged F1 scores between 85.0 and 92.0 across domains, outperforming supervised baselines and matching inter-annotator agreement. These findings establish a scalable foundation for AI-driven evaluation of physician-patient communication in oncology and beyond.

Indexed as

artificial intelligencelarge language modelsnatural language processingphysician-patient communicationProstate cancerrisk communicationshared decision-making

Identifiers

PMID40832413
PMCPMC12363684

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.