Evidence map›Paper›PMID 40832255›Full record

ArticlebioRxiv : the preprint server for biology2025

Short-term synaptic dynamics in the ventrolateral and dorsomedial periaqueductal gray.

A V Castro Romero, K A Tyner, J N Carroll, C E Vaaga

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

A V Castro RomeroDepartment of Biomedical Sciences, Colorado State University Fort Collins CO 80523.ORCID 0000-0003-0417-0210
K A TynerDepartment of Microbiology, Immunology, and Pathology, Colorado State University Fort Collins CO 80523.ORCID 0000-0002-5248-4241
J N CarrollDepartment of Biomedical Sciences, Colorado State University Fort Collins CO 80523.ORCID 0009-0009-8348-4832
C E VaagaDepartment of Biomedical Sciences, Colorado State University Fort Collins CO 80523.ORCID 0000-0001-9777-3808

Funding

Cerebellar Modulation of Innate Defensive BehaviorsR00NS119783 · NINDS · COLORADO STATE UNIVERSITY · PI VAAGA, CHRISTOPHER EDWARD · 2023 to 2025
$916k
NINDS NIH HHS R00 NS119783
6 · The paper itself

Abstract

The ability to assess and rapidly respond to predator threats in the environment is necessary for survival and requires dedicated neural circuits for threat detection, sensorimotor integration, and execution of ethologically appropriate behavioral responses. Although numerous brain circuits are involved in these processes, the midbrain periaqueductal gray (PAG) serves as an important central hub to generate ethologically appropriate passive and/or active defensive behaviors. Despite its central role in generating defensive behaviors, little is known about the intrinsic and synaptic properties of neurons across columns in the PAG. To address this knowledge gap, we made whole-cell voltage- and current-clamp recordings from unlabeled neurons in the vl- and dmPAG of mice. Consistent with

Indexed as

fear circuitsinnate fearintrinsic propertiesperiaqueductal graysynaptic transmission

Identifiers

PMID40832255
PMCPMC12363969

What OpenQuestion holds

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LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.