Evidence map›Paper›PMID 40832192›Full record

ArticlebioRxiv : the preprint server for biology2025

Transient ion-mediated interactions regulate subunit rotation in a eukaryotic ribosome.

George Wanes, Udayan Mohanty, Paul Whitford

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors.

George WanesCenter for Theoretical Biological Physics, Northeastern University, Boston.
Udayan MohantyDepartment of Chemistry, Boston College, Chestnut Hill.
Paul WhitfordCenter for Theoretical Biological Physics, Northeastern University, Boston.ORCID 0000-0001-7104-2265

Funding

Elucidating the mechanisms that enable translation in bacterial and eukaryotic ribosomesR35GM153502 · NIGMS · NORTHEASTERN UNIVERSITY · PI Paul Charles Whitford · 2024 to 2026
$1.3M
NIGMS NIH HHS R35 GM153502
6 · The paper itself

Abstract

While it is known that ions are required for folding of RNA, little is known about how transient/probabilistic ionic interactions facilitate biologically-relevant conformational rearrangements. To address this, we developed a theoretical model that employs all-atom resolution, with a simplified representation of biomolecular energetics, explicit electrostatics and ions (K

Identifiers

PMID40832192
PMCPMC12363776

What OpenQuestion holds

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LicenceCC BY-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.