ReviewFrontiers in cardiovascular medicine2025
Physiologic effects of different hemodynamic patterns of LVAD.
Review in Frontiers in cardiovascular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Pulsatility as a Potential Regulator of Cardiovascular Biology: Molecular, Cellular, and Hemodynamic Remodeling During Continuous-Flow Left Ventricular Assist Device Support and Following Heart Transplantation.International journal of molecular sciences · 2026Review
- Beyond Continuous-Flow: The Next Wave of Fully Implantable LVADs and Total Artificial Hearts.Current heart failure reports · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Left ventricular assist device (LVAD) is an important treatment for patients with end-stage heart failure, which essentially replaces the left ventricle's pumping action to improve peripheral circulation. Its hemodynamic pattern (pulsatile vs. continuous flow) has been a popular research topic in the field. Because of its dependability and endurance, the continuous flow LVAD (CFVAD), as opposed to the first generation of pulsatile flow LVAD (PFVAD), has gained popularity as a mechanical support device in clinical practice in recent years. Many of the complications that arise with CFVAD application are thought to be related to reduced pulsatility. This article provides a review of the physiologic effects of different hemodynamic patterns on the circulatory system and the difference in outcomes of PFVAD vs. CFVAD.
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Registered trials
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