ArticleCureus2025
Impact of Early Rehabilitation Initiation on Walking Recovery in Critically Ill Patients.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Characteristics and Progression of Rehabilitation in Patients Undergoing Extracorporeal Membrane Oxygenation: A Retrospective Study.Clinical transplantation · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose Predicting walking recovery in critically ill patients, including the timing of early rehabilitation, remains unclear. This study aimed to identify clinical factors, particularly the timing of first sitting on the edge of the bed, that are associated with walking recovery in critically ill patients. Methods We retrospectively analyzed data from mechanically ventilated patients (≥48 hours) admitted to the intensive care unit (ICU) of a tertiary-care hospital. Only patients who survived until hospital discharge were included. Walking recovery was defined as achieving a Functional Ambulation Categories (FAC) score ≥ 3, indicating independent walking on level ground with supervision for safety. Results A total of 121 patients were included. The median age was 73 years, 83 (68.6%) were male, the mean Acute Physiology and Chronic Health Evaluation II (APACHE II) score was 18.9 ± 6.5, and the median duration of mechanical ventilation was seven days. Cox proportional-hazards regression identified three independent predictors of walking recovery: younger age (hazard ratio (HR) 0.98; 95% CI 0.97-1.00; p = 0.016), shorter duration of mechanical ventilation (HR 0.97; 95% CI: 0.95-1.00; p = 0.049), and sitting on the edge of the bed within 13 days (HR 0.11; 95% CI 0.52-0.91; p < 0.001). Receiver operating characteristic (ROC) analysis identified day 13 as the optimal cutoff for sitting, with an area under the curve (AUC) of 0.76, sensitivity of 81.6%, and specificity of 67.4% for predicting walking recovery. Gray's test further demonstrated that initiating sitting after 13 days significantly reduced the probability of walking recovery compared to earlier initiation (p < 0.001). Conclusion Achieving a sitting position at the edge of the bed by day 13 may serve as a clinically relevant marker for timely rehabilitation initiation and improved walking recovery in critically ill patients. However, the timing for initiating sitting on the edge of the bed should be validated through future prospective multicenter studies.
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