ArticleFrontiers in pediatrics2025
Semiquantitative chest computed tomography scoring system to estimate severity in pediatric community-acquired pneumonia.
Article in Frontiers in pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: A retrospective study assessed the utility of semiquantitative chest Computed tomography (CT) in diagnosing and determining the severity of community acquired pneumonia (CAP) in children. Methods: The study included pediatric patients with CAP from January 2019 to December 2023. A semiquantitative chest CT scoring system was used based on the extent of lung inflammatory lesions and hydrothorax. The inter-rater reliability between two observers was assessed. The score was then correlated with laboratory results, identified pathogens, and patient prognosis. Receiver operating characteristic (ROC) analysis was employed to evaluate the diagnostic accuracy of the score for identifying severe cases. Results: The study included 426 patients, with 186 severe cases (43.66%). The intragroup correlation coefficient (ICC) value of the two observers was 0.957 (95% Cl: 0.944-0.970). The results showed a positive correlation between chest CT scores and neutrophil percentage, neutrophil count, and C-reactive protein, procalcitonin, lactate dehydrogenase, and fibrinogen levels and a negative correlation between lymphocyte count and hemoglobin and albumin levels ( Conclusion: It is practicable and effective that a semiquantitative chest CT scoring system be used for estimating condition and evaluating prognosis of pediatric CAP.
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