Evidence map›Paper›PMID 40831667›Full record

ArticleGynecologic oncology reports2025

Risk factors for delayed diagnosis of endometrial cancer among black individuals: Results from the GUIDE-EC study.

Maya E Gross, Mindy Pike, Julianna Alson, Patrice Williams, Mollie E Wood, Erica Marsh, Erin Carey, Til Stürmer, Ronit Katz, Whitney R Robinson and 1 more

Abstract read
In one paragraph

Article in Gynecologic oncology reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Maya E GrossDepartment of Obstetrics and Gynecology, Fred Hutchinson Cancer Center, University of Washington, USA.
Mindy PikeDepartment of Obstetrics and Gynecology, Fred Hutchinson Cancer Center, University of Washington, USA.
Julianna AlsonDepartment of Obstetrics and Gynecology, Fred Hutchinson Cancer Center, University of Washington, USA.
Patrice WilliamsDepartment of Obstetrics and Gynecology, Fred Hutchinson Cancer Center, University of Washington, USA.
Mollie E WoodDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, USA.
Erica MarshDepartment of Obstetrics and Gynecology, School of Medicine, University of Michigan, USA.
Erin CareyDepartment of Obstetrics and Gynecology, School of Medicine, University of North Carolina, USA.
Til StürmerDepartment of Epidemiology, Gillings School of Global Public Health, University of North Carolina, USA.
Ronit KatzDepartment of Obstetrics and Gynecology, Fred Hutchinson Cancer Center, University of Washington, USA.
Whitney R RobinsonDepartment of Obstetrics and Gynecology, School of Medicine, Duke University, USA.
Kemi M DollDepartment of Obstetrics and Gynecology, Fred Hutchinson Cancer Center, University of Washington, USA.

Funding

TRAINING IN CANCER BIOLOGY &TRANSPLANTATIONT32CA009515 · NCI · UNIVERSITY OF WASHINGTON · PI NANCY ELLEN DAVIDSON, Effie W Petersdorf · 1985 to 2026
$16.2M
NCI NIH HHS T32 CA009515
6 · The paper itself

Abstract

Objective: Black patients with endometrial cancer (EC) experience disproportionately advanced stage at diagnosis. We aimed to identify variables, beyond race and histologic subtype, which increase risk for delayed diagnosis of EC. Methods: This is a retrospective study of Black individuals with EC in a large academic-affiliated healthcare system from 2014 to 2020. Primary outcome was delayed diagnosis of EC, defined as prolonged time to diagnosis (>28 days to reach diagnosis). We used descriptive statistics, univariate regression, and factor analysis to identify variables associated with delayed diagnosis, achieve data reduction, and calculate odds ratios for delayed diagnosis. Results: Of 388 patients with EC included for analysis, one fifth (n = 79, 20 %) experienced delayed diagnosis. Ultrasound had the strongest association with delayed diagnosis in univariate regression (OR 4.4, 95 % CI 2.4, 7.8) and factor analysis (OR 2.2, 95 % CI 1.6, 3.0). BMI ≥ 40 (OR 1.9, 95 % CI 1.1, 3.3) was also associated with delayed diagnosis. Age ≥ 50 was associated with decreased odds of delayed diagnosis (OR 0.3, 95 % CI 0.2, 0.7). Presence of an endometrial biopsy was associated with decreased odds of delayed diagnosis on univariate regression (OR 0.4, 95 % CI 0.2, 1.4). Conclusions: A fifth of Black patients with EC experienced delayed diagnosis, and preoperative ultrasound was most strongly associated with delayed diagnosis. Providers should consider a tissue-sampling-first approach in Black patients at risk for EC.

Indexed as

DiagnosisEndometrial cancerHealthcare qualityRacial disparitiesTransvaginal ultrasound

Identifiers

PMID40831667
PMCPMC12359182

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.