Evidence map›Paper›PMID 40831564›Full record

ArticleFrontiers in immunology2025

Mice mucosal leishmaniasis model shown high parasite load, increased cytotoxicity and impaired IL-10

Alisson Amaral Da-Rocha, Júlio Souza Dos-Santos, Igor Santos Bittencourt, Douglas B De-Almeida, Naiara Carla Dos Santos Manhães, Hozany Praxedes, João Victor Paiva Romano, Elias Barbosa da Silva-Junior, Antônio José da Silva-Gonçalves, Marcia Pereira Oliveira and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Alisson Amaral Da-RochaInstituto de Microbiologia Paulo de Góes - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Júlio Souza Dos-SantosInstituto de Microbiologia Paulo de Góes - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Igor Santos BittencourtInstituto de Microbiologia Paulo de Góes - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Douglas B De-AlmeidaInstituto de Microbiologia Paulo de Góes - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Naiara Carla Dos Santos ManhãesInstituto de Microbiologia Paulo de Góes - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Hozany PraxedesInstituto de Microbiologia Paulo de Góes - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
João Victor Paiva RomanoInstituto de Microbiologia Paulo de Góes - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Elias Barbosa da Silva-JuniorInstituto de Biofísica Carlos Chagas Filho - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Antônio José da Silva-GonçalvesLaboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Marcia Pereira OliveiraLaboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Luciana Polaco CovreNúcleo de Doenças Infecciosas - Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil.
Daniel Claudio de Oliveira GomesNúcleo de Doenças Infecciosas - Universidade Federal do Espírito Santo, Vitória, Espírito Santo, Brazil.
Alda Maria Da-CruzLaboratório Interdisciplinar de Pesquisas Médicas, Instituto Oswaldo Cruz, Fundação Oswaldo Cruz, Rio de Janeiro, Brazil.
Alessandra Marcia da Fonseca-MartinsInstituto de Microbiologia Paulo de Góes - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.
Herbert Leonel de Matos GuedesInstituto de Microbiologia Paulo de Góes - Universidade Federal do Rio de Janeiro, Rio de Janeiro, Rio de Janeiro, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Mucosal Leishmaniasis is one of the most aggressive clinical manifestations of

Indexed as

Interleukin-10LeishmaniaLeishmaniasis, MucocutaneousTh17 CellsAnimalsDisease Models, AnimalFemaleMiceMice, Inbred BALB CParasite LoadIL10 protein, mouseInterleukin-10BALB/cexperimental infectionL. amazonensisleishmaniasismucosa

Identifiers

PMID40831564
PMCPMC12358393

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.