Evidence map›Paper›PMID 40831561›Full record

ArticleFrontiers in immunology2025

Phenotypically distinguishable eosinophilic cells do not impact epithelial functions in a triple-culture

Christoph Benkstein, Laurin Mosig, Daniel Vondran, Heidi Schlichting, Lea Kissing, Bente Wohlert, Ida Gensmer, Larissa Nogueira de Almeida, Peter König, Kerstin Fibelkorn and 4 more

Abstract read
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Christoph Benkstein *Institute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Laurin Mosig *Institute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Daniel VondranInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Heidi SchlichtingInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Lea KissingInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Bente WohlertInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Ida GensmerInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Larissa Nogueira de AlmeidaInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Peter KönigInstitute of Anatomy, University of Lübeck, Lübeck, Germany.
Kerstin FibelkornInstitute of Anatomy, University of Lübeck, Lübeck, Germany.
Anna KordowskiInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Stefanie Derer-PetersenInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Christian SinaInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.
Yves LaumonnierInstitute of Nutritional Medicine, Hospital Schleswig-Holstein (UKSH), Lübeck, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The small intestine is a complex assembly of different cell types, such as enterocytes, secretory, immune, stromal and nervous cells. Due to this complexity, studying human tissue function

Indexed as

EosinophilsEpithelial CellsIntestinal MucosaCaco-2 CellsCell DifferentiationCoculture TechniquesHT29 CellsHumansPhenotypeCaco-2electron microscopyeosinophilsHT29-MTX cellstriple culture system

Identifiers

PMID40831561
PMCPMC12358489

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.