Evidence map›Paper›PMID 40831550›Full record

ArticleBJUI compass2025

Comparison of p-Tm:YAG, TFL and Ho:YAG's in vitro ablation rates on synthetic and human stones.

Frédéric Panthier, Alba Sierra, Etienne Xavier Keller, Marie Chicaud, Eugenio Ventimiglia, Jia-Lun Kwok, Vincent De Coninck, Mariela Corrales, Michel Daudon, Cyril Gorny and 4 more

Abstract read
In one paragraph

Article in BJUI compass, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Frédéric PanthierSorbonne University GRC Urolithiasis no. 20, Tenon Hospital Paris France.ORCID https://orcid.org/0000-0003-3055-2984
Alba SierraProgressive Endourological Association for Research and Leading Solutions (PEARLS) Paris France.ORCID https://orcid.org/0000-0003-2474-8067
Etienne Xavier KellerProgressive Endourological Association for Research and Leading Solutions (PEARLS) Paris France.ORCID https://orcid.org/0000-0003-1667-7609
Marie ChicaudSorbonne University GRC Urolithiasis no. 20, Tenon Hospital Paris France.
Eugenio VentimigliaProgressive Endourological Association for Research and Leading Solutions (PEARLS) Paris France.ORCID https://orcid.org/0000-0003-3654-1629
Jia-Lun KwokProgressive Endourological Association for Research and Leading Solutions (PEARLS) Paris France.ORCID https://orcid.org/0000-0002-9758-6225
Vincent De ConinckProgressive Endourological Association for Research and Leading Solutions (PEARLS) Paris France.
Mariela CorralesSorbonne University GRC Urolithiasis no. 20, Tenon Hospital Paris France.ORCID https://orcid.org/0000-0002-1461-8464
Michel DaudonSorbonne University GRC Urolithiasis no. 20, Tenon Hospital Paris France.
Cyril GornyPIMM UMR 8006 CNRS-Arts et Métiers ParisTech Paris France.
Steeve DoiziSorbonne University GRC Urolithiasis no. 20, Tenon Hospital Paris France.
Laurent BerthePIMM UMR 8006 CNRS-Arts et Métiers ParisTech Paris France.
Daron SmithDepartment of Urology Westmoreland Street Hospital, UCLH NHS Foundation Trust London UK.ORCID https://orcid.org/0000-0001-8314-4795
Olivier TraxerSorbonne University GRC Urolithiasis no. 20, Tenon Hospital Paris France.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To compare in vitro the ablation rates of p-Tm:YAG, TFL and Ho:YAG against synthetic and human stones. Material and Methods: p-Tm:YAG, TFL and Low-Power (LP) Ho:YAG were compared using 270 μm core-diameter laser fibres (CDF); experiments with 200 μm(p-Tm:YAG) and 150 μm-CDF (TFL) were also included. A continuous laser emission was applied through a spiral trajectory for 20 seconds with the laser fibre tip in contact with synthetic hard (HSP) and soft stone phantoms (SSP) submerged in saline. "Dusting" settings for p-Tm:YAG(0,6 J-20 Hz-Flex Long Pulse), TFL(0,5 J-30 Hz-Short Pulse) and Ho:YAG(0,5 J-30 Hz-Long Pulse) and "Fragmentation" settings for p-Tm:YAG(1 J-15 Hz-Captive), TFL(1 J-15 Hz-Short Pulse) and Ho:YAG(1 J-15 Hz-Long Pulse) were analysed. Then, experiments for human calcium oxalate monohydrate (COM), uric acid (UA) and cystine (CYS) stones were performed with single laser pulses at 0.6 J, 0.8 J and 1.0 J for p-Tm:YAG (Captive Fragmenting mode), TFL (Short Pulse) and Ho:YAG (Long Pulse). Synthetic and human stone samples were dried before three-dimensional scanning to measure ablation rates (ARs) and ablation volume per pulse (AVP). Results: For synthetic stones with 270 μm-CDF, the p-Tm:YAG and TFL presented similar ARs, except in Fragmentation against HSP (95,1 ± 13,6vs67 ± 14 p = 0,02, respectively). Both p-Tm:YAG and TFL achieved higher ARs than Ho:YAG in all settings. p-Tm:YAG-200 μm-CDF and TFL-150 μm-CDF presented similar ARs, except in Fragmentation against HSP(78,4 ± 8vs42,5 ± 2,6 mm Conclusion: p-Tm:YAG and TFL achieved higher ARs than LP-Ho:YAG against synthetic stones in vitro. For human stones, TFL achieved the highest AVP against COM while LP-Ho:YAG delivered higher AVPs against UA and CYS, for which TFL performed worst.

Indexed as

Holmium:YAGlaserlithotripsypulsed Thulium:YAGThulium Fibre Laserureteroscopy

Identifiers

PMID40831550
PMCPMC12360892

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.