Evidence map›Paper›PMID 40831549›Full record

ArticleCurrent directions in psychological science2025

More than just a phase: adolescence as a window into how the brain generates behavior.

Catherine Insel, Alexandra O Cohen

Abstract read
In one paragraph

Article in Current directions in psychological science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Striatal and hippocampal contributions to value-based learning in adolescence.Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Catherine InselDepartment of Psychology, Institute for Policy Research, Northwestern University.
Alexandra O CohenDepartment of Psychology, Emory University.

Funding

Neurocognitive mechanisms of reward - motivated memory persistence across ageK01DA053438 · NIDA · NEW YORK UNIVERSITY · PI Alexandra Cohen · 2022 to 2026
$875k
Computational and neurodevelopmental mechanisms of memory-guided decision-makingR00MH133994 · NIMH · NORTHWESTERN UNIVERSITY · PI Catherine Insel · 2025 to 2026
$491k
Computational and neurodevelopmental mechanisms of memory-guided decision-makingK99MH133994 · NIMH · COLUMBIA UNIV NEW YORK MORNINGSIDE · PI INSEL, CATHERINE · 2023 to 2024
$262k
NIDA NIH HHS K01 DA053438NIMH NIH HHS K99 MH133994NIMH NIH HHS R00 MH133994
6 · The paper itself

Abstract

Adolescence is a dynamic period of brain development, marked by profound changes in learning, decision-making, and higher-order cognition. This review explores how research on the adolescent brain can inform the development of biologically-based computational models of learning and behavior. We highlight how computational frameworks such as reinforcement learning (RL) and artificial neural networks (ANNs) capture key features of adolescent behavior, including shifts in exploration and decision-making strategies. By integrating principles of brain development, such as synaptic pruning and hierarchical development of neural circuits, computational models can offer insights into how the brain adapts to new experiences and challenges. We argue that studying adolescent brain development not only enhances our understanding of cognition but also provides a valuable framework for refining computational models of brain function. We propose future directions for how adolescent research can inform innovations in computational research to better capture dynamic brain states, individual variability, and risk for psychopathology.

Indexed as

adolescencebehaviorbraincomputationneurodevelopment

Identifiers

PMID40831549
PMCPMC12360681

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.