Evidence map›Paper›PMID 40831512›Full record

ArticleResearch square2025

Fall risk in relation to strength training, walking, and sitting among women aged 75-105 years: a cross-sectional study within the Women's Health Initiative Strong and Healthy (WHISH) Intervention Cohort.

Corey Rovzar, Saachi Jhandi, Sally Mackey, Deepika Laddu, Sa Shen, Andrea LaCroix, Marcia L Stefanick

Abstract readPreprint
In one paragraph

Article in Research square, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Corey RovzarStanford University School of Medicine.
Saachi JhandiUniversity of Utah School of Medicine.
Sally MackeyStanford University School of Medicine.
Deepika LadduNorthwestern University.
Sa ShenStanford University.
Andrea LaCroixUniversity of California, San Diego.
Marcia L StefanickStanford University School of Medicine.

Funding

WOMEN'S HEALTH INITIATIVE - CLINICAL COORDINATING CENTER: TASK AREA B - LONG LIFE STUDY VISIT 2 LIMITED HOME VISIT75N92021D00001 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI ANDERSON, GARNET L. · 2021 to 2025
$52.0M
Women's Health Initiative Strong & Healthy (WHISH) NIA Exercise MaterialsU01HL122280 · NHLBI · STANFORD UNIVERSITY · PI STEFANICK, MARCIA L. · 2015 to 2019
$6.9M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC): TASK AREA A AND A275N92021D00002 · NHLBI · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI WACTAWSKI-WENDE, JEAN · 2021 to 2025
$6.9M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00004 · NHLBI · STANFORD UNIVERSITY · PI STEFANICK, MARCIA · 2021 to 2025
$6.5M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00003 · NHLBI · OHIO STATE UNIVERSITY · PI JACKSON, REBECCA · 2021 to 2025
$5.0M
WOMEN'S HEALTH INITIATIVE (WHI) REGIONAL CENTER (RC) - TO EXERCISE OPTION PERIOD ONE (1) AND REVISE CONTRACT ARTICLES.75N92021D00005 · NHLBI · WAKE FOREST UNIVERSITY HEALTH SCIENCES · PI VITOLINS, MARA · 2021 to 2025
$4.2M
Physical Activity to Improve CV Health in Older Women: A Pragmatic Trial -- DCCU01HL122273 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI KOOPERBERG, CHARLES L, LACROIX, ANDREA Z. · 2015 to 2019
$4.2M
Cardiovascular and Chronic Disease Prevention Training ProgramT32HL161270 · NHLBI · STANFORD UNIVERSITY · PI CHRISTOPHER D GARDNER · 2022 to 2026
$2.6M
NHLBI NIH HHS 75N92021D00001NHLBI NIH HHS 75N92021D00002NHLBI NIH HHS T32 HL161270NHLBI NIH HHS U01 HL122273NHLBI NIH HHS U01 HL122280WHI NIH HHS 75N92021D00003WHI NIH HHS 75N92021D00004WHI NIH HHS 75N92021D00005
6 · The paper itself

Abstract

Background: Falls are the leading cause of injury and injury death among older women in the United States. The Women's Health Initiative Strong and Healthy ( Methods: We analyzed data from 8,915 women aged 75-105 years (mean age 84.9 ± 5.1 years; 49.6% ≥85 years) randomly assigned to a PA intervention in the Results: Mean age was 84.9 years, with 49.6% of participants aged ≥ 85 years. FR-ABC classification was 35.1% overall, 22.7% for women aged 75-84 and 47.4% for women aged ≥ 85 years. Overall, strength training ≥ 2 hours per week was associated with a 34% FR-ABC risk reduction (RR = 0.66, 95% CI: 0.61-0.71); walking ≥ 4.25 hours/week with a 70% FR-ABC risk reduction (RR = 0.30, 95% CI: 0.27-0.33); while, sitting ≥ 8 hours/day was associated with a 41% increased FR-ABC risk (RR = 1.41, 95% CI: 1.33-1.49). High PF (score ≥ 90) was associated with a 91% FR-ABC risk reduction (p < 0.001). Conclusion: More strength training and walking, lower sitting time, and higher PF were strongly associated with reduced fall risk classification among women aged 75 years and older. Although these associations were more pronounced among women aged 75-84 year, it was also true for women aged 85 and over. Fall risk prevention should emphasize each of these PA factors.

Indexed as

Balancebalance confidencefall riskfallsPAphysical function

Identifiers

PMID40831512
PMCPMC12363929

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.