Evidence map›Paper›PMID 40831364›Full record

SynthesisPrehospital and disaster medicine2025

Emergency Care Interventions for Victims of Explosive Ordnance Reduce Mortality: A Modeling Study.

Hannah B H Wild, Benjamin Q Huynh, Sebastian Kasack, Alex Munyambabazi, Yves Sanou, Yves Nacanabo, Moumini Niaone, Aparna Cheran, Emilie Calvello Hynes, Nicolas Meda and 2 more

Abstract readMeta-Analysis
In one paragraph

Synthesis in Prehospital and disaster medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Hannah B H WildDepartment of Surgery, University of Seattle, Washington, USA.ORCID 0000-0003-0974-0956
Benjamin Q HuynhDepartment of Environmental Health and Engineering, Johns Hopkins University, Baltimore, Maryland, USA.
Sebastian KasackMines Advisory Group, Manchester, United Kingdom.
Alex MunyambabaziAmputee Self Help Network Uganda, Kampala, Uganda.
Yves SanouCaptain Halassane Coulibaly Military Hospital, Ouagadougou, Burkina Faso.
Yves NacanaboCaptain Halassane Coulibaly Military Hospital, Ouagadougou, Burkina Faso.
Moumini NiaoneDepartment of Public Health, University of Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.
Aparna CheranExplosive Weapons Trauma Care Collective, International Blast Injury Research Network, University of Southampton, Southampton, United Kingdom.
Emilie Calvello HynesWorld Health Organization, Geneva, Switzerland.
Nicolas MedaDepartment of Public Health, University of Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.
Adam KushnerExplosive Weapons Trauma Care Collective, International Blast Injury Research Network, University of Southampton, Southampton, United Kingdom.
Barclay T StewartDepartment of Surgery, University of Seattle, Washington, USA.

Funding

Research Mentoring and Building Capacity of underrepresented Minority Research Scientists in India.D43TW010540 · FIC · YALE UNIVERSITY · PI MICHELE BARRY, Eva Harris · 2017 to 2026
$15.5M
FIC NIH HHS D43 TW010540World Health Organization 001
6 · The paper itself

Abstract

backgroundModern conflicts are characterized by wide-spread use of conventional explosive ordnance (EO), improvised explosive devices (IEDs), and other air-launched explosives. In contrast to advances in military medicine and high-income civilian trauma systems since the United States-led wars in Afghanistan and Iraq, the mortality rate among civilian EO casualties has not decreased in decades. Although humanitarian mine action (HMA) stakeholders have extensive presence and medical capabilities in EO-affected settings, coordination between HMA and health actors has not been leveraged systematically.

methodsData from a prior systematic review of emergency care interventions feasible within the context of HMA activities and low-resource health care systems were used to model mortality reduction among EO victims. Interventions were categorized using the World Health Organization (WHO) Emergency Care System Framework sites of "scene," "transport," and "facility." The cumulative impact of the interventions on EO-related mortality was estimated using pooled effect estimates and simulation modeling.

resultsThe meta-analysis included 16 reports from 13 countries, representing 127,505 injured persons. Pooled effect estimates across subcategories of emergency care interventions were 0.42 for layperson transportation (95%CI, 0.24-0.74), 0.79 for prehospital notification systems (95%CI, 0.51-1.19), 0.52 for prehospital trauma care training courses (95%CI, 0.46-0.59), 0.67 for facility-based trauma care training courses (95%CI, 0.48-0.92), and 0.66 for facility-based trauma team organization and activation protocols (95%CI, 0.45-0.97). A 68% reduction in mortality (95%UI, 57%-79%) was observed when implementing the full set of interventions in a region with no prior implemented interventions.

conclusionEnhanced coordination between HMA and health actors to implement a structured set of emergency care interventions holds potential to significantly reduce preventable death among civilian EO casualties.

Indexed as

Blast InjuriesEmergency Medical ServicesHumansblast injurycivilian casualtiesconflictemergency careemergency care systemsexplosive ordnanceexplosive weaponshumanitarian mine actionlow-resource settingstrauma care

Identifiers

PMID40831364
PMCPMC12809202

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.