Evidence map›Paper›PMID 40831266›Full record

ArticleChemistryOpen2025

Azobenzene DNA Intercalator/Cyclodextrin Pseudo-Rotaxane: From Photoswitchable Chirality and Fluorescence to DNA Melting Control.

Olivier Abodja, Astrid Walrant, Sergii Rudiuk, Mathieu Morel, Damien Baigl

Abstract read
In one paragraph

Article in ChemistryOpen, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Olivier AbodjaCPCV, Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 75005, Paris, France.ORCID 0009-0006-0774-8398
Astrid WalrantCPCV, Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 75005, Paris, France.ORCID 0000-0003-4054-905X
Sergii RudiukCPCV, Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 75005, Paris, France.ORCID 0000-0003-1728-1163
Mathieu MorelCPCV, Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 75005, Paris, France.ORCID 0000-0002-6284-1708
Damien BaiglCPCV, Department of Chemistry, Ecole Normale Supérieure, PSL University, Sorbonne Université, CNRS, 75005, Paris, France.ORCID 0000-0003-1772-3080

Funding

Agence Nationale de la Recherche ANR-18-CE06-0019Agence Nationale de la Recherche ANR-21-CE18-0051FP7 Ideas: European Research Council 258782HORIZON EUROPE European Research Council 101096956Institut Universitaire de France
6 · The paper itself

Abstract

Pseudo-rotaxanes are reversibly interlocked molecules with at least one linear molecule threaded into a macrocycle and, contrary to rotaxanes, an advantageous ability to be dissociated. Cyclodextrins constitute attracting macrocyclic host entities to build such dynamic structures for their oligosaccharide nature, conic shape, amphiphilic character and biocompatibility. Here we show that using an azobenzene DNA intercalator as a guest allows to build a pseudo-rotaxane combining several remarkable properties, including light-controlled assembly/disassembly, photoreversible chirality and fluorescence, as well as the capability to affect the melting temperature of double-stranded DNA through intercalator host-guest complexation.

Indexed as

Azo CompoundsCyclodextrinsDNAIntercalating AgentsRotaxanesFluorescenceNucleic Acid DenaturationStereoisomerismazobenzeneAzo CompoundsCyclodextrinsDNAIntercalating AgentsRotaxanesDNA hybridizationDNA nanotechnologyhost‐guestphotoswitchsupramolecular chemistry

Identifiers

PMID40831266
PMCPMC12680564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.