Evidence map›Paper›PMID 40831222›Full record

ArticleBritish journal of clinical pharmacology2025

Patient preferences and attitudes regarding the environmental impact of medicines: A discrete choice experiment.

Milad Sadreghaemy, Daphne Philbert, Eibert R Heerdink, Marcel L Bouvy, Toine C G Egberts, Lourens T Bloem

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Article in British journal of clinical pharmacology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Milad SadreghaemyDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0009-0007-5048-4954
Daphne PhilbertDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0001-6734-528X
Eibert R HeerdinkDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-5946-7209
Marcel L BouvyDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-4596-0684
Toine C G EgbertsDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0003-1758-7779
Lourens T BloemDivision of Pharmacoepidemiology and Clinical Pharmacology, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands.ORCID https://orcid.org/0000-0002-0014-8625

Funding

Sawtooth Software
6 · The paper itself

Abstract

aimsPharmaceutical utilization within global healthcare has significant environmental impact throughout its lifecycle. Understanding how the environmental impact of medicines influences patients' preferences relative to ease of use and cost supports interventions promoting appropriate medicine consumption, reduced waste and environmental sustainability. The aim of this study was to investigate patient preferences and attitudes regarding the environmental impact of medicines in relation to ease of use and cost.

methodsA cross-sectional survey (December 2022 to January 2023) was conducted using the Dutch AMP pharmacy panel (>25 000 chronic medicine users). It included a discrete choice experiment (DCE) on medicines' environmental impact, ease of use and cost, and questions on environmental sustainability in medicine use and daily life. Latent class analysis identified groups with shared preferences. An environmental sustainability attitude score was calculated from daily life behaviour.

resultsOf 25 787 invited panel members 6390 responded and 4122 were included in the analysis (16.0%, mean age 68 years, 42.6% female). Four preference groups were identified and labelled based on DCE-derived attribute preferences: eco-focused (55.7%), cost-focused (20.1%), indifferent (16.4%) and eco-sceptical (7.8%). Environmental sustainability attitude scores were highest in the eco-focused and eco-sceptical (median 75.0%) groups, followed by the indifferent and cost-focused (median 66.7%) groups. Important factors influencing this were environmental concerns (eco-focused), environmental and personal health concerns (eco-sceptical), costs (cost-focused) and environmental, cost and personal health concerns (indifferent). Only 8.8-15.5% reported good or very good self-assessed knowledge of medicines' environmental impact.

conclusionsEnvironmental sustainability significantly affects medicine preferences, although heterogeneity exists. Tailored initiatives are required to promote environmentally sustainable pharmaceutical care.

Indexed as

EnvironmentPatient PreferenceAdultAgedChoice BehaviorCross-Sectional StudiesFemaleHumansMaleMiddle AgedNetherlandsSurveys and Questionnairesdiscrete choice experimentenvironmental impactmedicine wastepatient preferencespharmaceutical caresustainable medicine usesustainable pharmacy

Identifiers

PMID40831222
PMCPMC12464640

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.