Evidence map›Paper›PMID 40831169›Full record

ArticleZhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics2025

[Correlation between bone mineral density and bone metabolic markers in preschool children and the influencing factors for bone mineral density].

Luopa Ni, Ailipati Tailaiti, Kereman Paerhati, Min-Nan Wang, Yan Guo, Zumureti Yimin, Gulijianati Abulakemu, Rena Maimaiti

Abstract readEnglish Abstract
PubMed Full text at PMC Publisher
In one paragraph

Article in Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Luopa NiDepartment of Child Health Care, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Ailipati Tailaiti
Kereman PaerhatiDepartment of Child Health Care, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Min-Nan WangDepartment of Child Health Care, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Yan GuoDepartment of Child Health Care, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Zumureti YiminDepartment of Child Health Care, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Gulijianati AbulakemuDepartment of Child Health Care, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.
Rena MaimaitiDepartment of Child Health Care, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo investigate the correlation between bone mineral density (BMD) and bone metabolic markers in preschool children and the influencing factors for BMD, and to provide a clinical basis for promoting bone health in children.

methodsA retrospective analysis was performed for the data of 127 preschool children who underwent physical examination in the Department of Child Health Care of the First Affiliated Hospital of Xinjiang Medical University, from June to December 2024. BMD and bone metabolic markers were measured, and physical examination was performed. A multiple linear regression analysis was used to investigate the effect of general information on BMD Z-score in preschool children. Spearman's rank correlation test was used to investigate the correlation of BMD Z-score with 25-hydroxyvitamin D (25-OHD), serum bone Gla protein (BGP), and parathyroid hormone (PTH).

resultsBMD Z-score significantly differed by ethnicity, weight category, and height category (all

conclusionsWeight, height, 25-OHD, BGP, and PTH are influencing factors for BMD in preschool children. In clinical practice, combined measurement of bone metabolic markers may provide a scientific basis for early identification of children with abnormal BMD and prevention of osteoporosis and osteomalacia.

Indexed as

Bone and BonesBone DensityBiomarkersBody WeightCalcium-Binding ProteinsChild, PreschoolExtracellular Matrix ProteinsFemaleHumansInfantLinear ModelsMaleMatrix Gla ProteinOsteocalcinParathyroid HormoneRetrospective Studies25-hydroxyvitamin DBiomarkersCalcium-Binding ProteinsExtracellular Matrix ProteinsMatrix Gla ProteinOsteocalcinParathyroid HormoneVitamin D25-Hydroxyvitamin DBone Gla proteinBone mineral densityChildParathyroid hormone

Identifiers

PMID40831169
PMCPMC12369536

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.