Evidence map›Paper›PMID 40831155›Full record

ReviewMicrobial biotechnology2025

Treatment of Clinically Important Bacteria With Cold Atmospheric Plasma.

Ruolan Ding, Jiajun Song, Xiaonan Huang, Li Tan, Xiancai Rao, Yi Yang

Abstract readReview
In one paragraph

Review in Microbial biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ruolan DingDepartment of Microbiology, School of Medicine, Chongqing University, Chongqing, China.
Jiajun SongCollege of Basic Medical Sciences, Army Medical University, Chongqing, China.
Xiaonan HuangDepartment of Microbiology, College of Basic Medical Sciences, Army Medical University, Key Laboratory of Microbial Engineering Under the Educational Committee in Chongqing, Chongqing, China.
Li TanDepartment of Microbiology, College of Basic Medical Sciences, Army Medical University, Key Laboratory of Microbial Engineering Under the Educational Committee in Chongqing, Chongqing, China.
Xiancai RaoDepartment of Microbiology, School of Medicine, Chongqing University, Chongqing, China.
Yi YangDepartment of Microbiology, College of Basic Medical Sciences, Army Medical University, Key Laboratory of Microbial Engineering Under the Educational Committee in Chongqing, Chongqing, China.

Funding

National Natural Science Foundation of China 82172321Natural Science Foundation of Chongqing CSTB2024NSCQ-MSX0513
6 · The paper itself

Abstract

Antimicrobial resistance (AMR), especially in clinically important bacteria, has posed serious challenges to clinical treatments. Novel and effective antimicrobial strategies are urgently needed to address AMR. Cold atmospheric plasma (CAP) is a new concept of disinfection method that kills bacteria through various active species and particles within an ionised and electrical-balanced gas. In this review, we introduced the generation of CAP and summarised its disinfection mechanisms. Moreover, we reviewed the applications of CAP in treating globally important bacteria, including Gram-positive bacteria such as Staphylococcus aureus, Enterococcus spp., Streptococcus pyogenes and Mycobacterium tuberculosis, as well as Gram-negative bacteria including Escherichia coli, Pseudomonas aeruginosa, Klebsiella pneumoniae, Acinetobacter baumannii and Neisseria gonorrhoeae. Additionally, we discussed technological strategies to enhance CAP disinfection efficacy and evaluated the safety of CAP applications. We recommend CAP as an effective alternative technology for combating bacterial infections and hope that the comprehensive information provided in the present review will facilitate the development of CAP-based disinfection strategies to overcome AMR issues in the future.

Indexed as

BacteriaBacterial InfectionsDisinfectionGram-Negative BacteriaGram-Positive BacteriaPlasma GasesHumansMicrobial ViabilityPlasma Gasesantibiotic‐resistance bacteriabactericidal mechanismscold atmospheric plasmainfectious disease controlsynergistic antimicrobial strategy

Identifiers

PMID40831155
PMCPMC12365345

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.