Evidence map›Paper›PMID 40831154›Full record

SynthesisWorld journal of surgery2025

Intestinal Intussusception in Adults: A Systematic Review.

Sidney Heersche, Jeanne Hirt, Fabio Butti, Martin Hübner, Dieter Hahnloser, Gaëtan-Romain Joliat, Fabian Grass

Abstract readSystematic Review
In one paragraph

Synthesis in World journal of surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Malignancy risk and management outcomes in adult intussusception: a single-institution retrospective study.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2026
    Article
  9. [Imaging diagnostics for diseases of the small bowel].Radiologie (Heidelberg, Germany) · 2026
    Review
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Sidney HeerscheDepartment of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.ORCID https://orcid.org/0009-0006-0618-8106
Jeanne HirtDepartment of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.
Fabio ButtiDepartment of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.
Martin HübnerDepartment of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.
Dieter HahnloserDepartment of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.
Gaëtan-Romain JoliatDepartment of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.
Fabian GrassDepartment of Visceral Surgery, Lausanne University Hospital CHUV, Lausanne, Switzerland.ORCID https://orcid.org/0000-0001-9884-2879

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundManagement of intestinal intussusception remains controversial with regards to conservative versus operative management, as well as choice of surgical procedure.

methodsA systematic review on PubMed/MEDLINE, Web of Science, Google Scholar, SCOPUS/EMBASE, and the Cochrane Library was performed. Articles published between 2004 and 2024 were collected. Case reports and case series < 20 patients were not considered.

resultsAfter screening of 2286 articles, 37 studies totaling 2330 patients were included. All studies were retrospective case series except for one prospective case series and one prospective and retrospective case series. There were 20% of colocolic intussusceptions, 21% of ileocolic intussusceptions, and 65% of enteric (small bowel) intussusceptions. A radiological lead point of the intussusception was described in 31% of patients. Intussusceptions were idiopathic in 39%, and caused by a pathological lead point in 58% of cases. Underlying malignancy was present 25% of cases and was more frequent in case of colocolic intussusceptions (68%), versus 9% in small bowel intussusceptions, and 46% of ileocolic intussusceptions. Operative management was performed in 49% of intussusceptions, mainly through open access (72%). Based on these findings, a comprehensive algorithm is provided to guide treatment decisions in adult patients with intussusception.

conclusionData regarding surgical management of the intussusception were heterogenous and poorly reported. In case of colic intussusception, a high degree of suspicion for an underlying malignancy is warranted, and in that regard, an oncological surgical resection without reduction is recommended. Enteric intussusception should be managed according to length, clinical presentation, and interoperative findings of lead points.

Indexed as

IntussusceptionAdultColonic DiseasesHumansIleal Diseasesintussusceptioninvaginationresectionsurgerytreatment

Identifiers

PMID40831154
PMCPMC12515024

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.