ArticleUltrasonography (Seoul, Korea)2025
Integration of high-frequency ultrasound with the Global Acne Grading System for prediction of treatment efficiency in acne vulgaris.
Article in Ultrasonography (Seoul, Korea), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
purposeThis study aimed to establish a novel acne scoring system (GAGS-HFUS) that combined the Global Acne Grading System (GAGS) with high-frequency ultrasound (HFUS), and to evaluate its predictive value for unfavorable treatment response in patients who have moderate-to-severe acne.
methodsThis prospective study recruited consecutive patients with mild-to-severe acne vulgaris. The GAGS-HFUS was developed based on the HFUS-detected morphological characteristics of acne and the GAGS facial region classification. Acne severity was assessed using both ultrasonic scales (the GAGS-HFUS, Sonographic Scoring System for Acne [SSSA], and Sonographic Scoring of Acne [SOS-Acne]) and a clinical scale (the Investigator Global Assessment [IGA]). Three months of followup were conducted in a subgroup of 34 patients with moderate-to-severe acne treated with oral isotretinoin. Univariate and multivariate Poisson regression analyses were conducted to determine the predictive value of GAGS-HFUS for unfavorable treatment response in this subgroup.
resultsOverall, 60 patients with mild-to-severe acne (mean age, 24 years; range, 16 to 34 years; 25 males) were enrolled. The GAGS-HFUS demonstrated substantial agreement with SOS-Acne (Spearman rank correlation coefficient [Rs], 0.864; kappa, 0.713) and IGA (Rs, 0.837; kappa, 0.660). In the follow-up cohort of 34 patients with moderate-to-severe acne, GAGS-HFUS score was identified as an independent predictor of unfavorable treatment response (risk ratio, 1.125; P=0.002). Its predictive performance (area under the receiver operating characteristic curve, 0.936; P<0.001) was superior to those of IGA and SOS-Acne.
conclusionGAGS-HFUS is an independent predictor of unfavorable treatment response in patients with moderate-to-severe acne, underscoring its value in the strategic management of acne.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.