Evidence map›Paper›PMID 40830954›Full record

Observational studyBMC medicine2025

"Have you considered that it could be burnout?"-psychologization and stigmatization of self-reported long COVID or post-COVID-19 vaccination syndrome.

Ronja Büchner, Christian Sander, Stephanie Schindler, Martin Walter, Carmen Scheibenbogen, Georg Schomerus

Abstract readObservational Study
In one paragraph

Observational study in BMC medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ronja BüchnerDepartment of Psychiatry and Psychotherapy, Medical Faculty, Leipzig University, Semmelweisstr. 10, Leipzig, 04103, Germany. Ronja.Buechner@medizin.uni-leipzig.de.
Christian SanderDepartment of Psychiatry and Psychotherapy, Medical Center, Leipzig University, Leipzig, Germany.
Stephanie SchindlerDepartment of Psychiatry and Psychotherapy, Medical Center, Leipzig University, Leipzig, Germany.
Martin WalterDepartment of Psychiatry and Psychotherapy, Jena University Hospital, Jena, Germany.
Carmen ScheibenbogenInstitute of Medical Immunology, Charité - Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität zu Berlin, Berlin, Germany.
Georg SchomerusDepartment of Psychiatry and Psychotherapy, Medical Faculty, Leipzig University, Semmelweisstr. 10, Leipzig, 04103, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPeople reporting long COVID (LC) or post-COVID-19 vaccination syndrome (PCVS) not only suffer from their symptoms but also from stigmatization. Despite ample account and characterization of stigma experiences so far, its mechanisms and consequences on health outcomes, and particularly the role of "psychologization" remain unclear.

methodsIn a cross-sectional observational study, we examined a large convenience sample of adults who report having LC or PCVS. We translated and adapted the "Long Covid Stigma Scale" to measure stigmatization. We measured generally perceived and personally experienced psychologization with newly developed scales/items. Outcome measures included disclosure concerns, loss of trust in medicine, life satisfaction, depression, anxiety, self-esteem, and loneliness. We calculated overall prevalences of stigma and psychologization and their correlations with the outcomes. Using mediation analysis with SEM, we tested the hypothesis that psychologization of LC and PCVS syndromes causes harm by increasing stigmatization.

resultsAltogether, N = 2053 individuals (68% reporting LC, 32% reporting PCVS) were included in the analyses. The overall prevalences of stigma experiences were high: 83% of those reporting LC and 90% of those reporting PCVS experienced stigma. Prevalences of perceived psychologization (LC: 87%, PCVS: 91%) and experienced psychologization (LC: 82%, PCVS: 87%) were similarly high. Both stigmatization and psychologization were positively correlated with disclosure concerns, loss of trust in medicine, depression, anxiety, and loneliness as well as negatively correlated with life satisfaction and self-esteem. Mediation analysis indicated that stigmatization mediated a relevant proportion of the relationship between psychologization and negative outcomes.

conclusionsPeople reporting LC or PCVS are subject to stigmatization and psychologization. From a patient perspective, psychologization appears to be an important driver of stigmatization and negative outcomes.

Indexed as

COVID-19COVID-19 VaccinesSocial StigmaAdultAgedAnxietyCross-Sectional StudiesDepressionFemaleHumansLonelinessMaleMiddle AgedSelf ConceptSelf ReportYoung AdultCOVID-19 VaccinesLong COVIDPost-COVID-19 vaccination syndromePost-COVID conditionPsychologizationStigmatization

Identifiers

PMID40830954
PMCPMC12366089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.