ArticleBMC pulmonary medicine2025
Relationship between cardiovascular health and COPD andits impact on all-cause mortality in patients with COPD: analyses of NHANES 2005-2018.
Article in BMC pulmonary medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Comparing the predictive accuracy of life's essential 8 and life's crucial 9 scores for all-cause mortality in COPD patients among US adults: a prospective cohort study.BMC public health · 2026Article
- Association of Life's Crucial 9 with asthma in U.S. adults: a cross-sectional study from National Health and Nutrition Examination Survey (NHANES).Journal of thoracic disease · 2025Article
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Authors and funding
4 authors.
Funding
Abstract
backgroundChronic obstructive pulmonary disease (COPD) and cardiovascular disease (CVD) are intimately connected. A recently developed measure called Life's Essential 8 (LE8) is used to evaluate cardiovascular health (CVH). We aimed to investigate the relationship between LE8 and the prevalence of COPD, and the association between LE8 and all-cause mortality in individuals with COPD.
methodsThe National Health and Nutrition Examination Survey (NHANES) 2005-2018 was the source of the data used in our investigation. The participants were divided into three groups according to their LE8 scores: low (< 50), moderate (50-79), and high (≥ 80) CVH. Weighted logistic regression models and restricted cubic spline (RCS) curves were used to examine the relationship between LE8 score and the prevalence of COPD. To determine whether the results were stable, we used subgroup and sensitivity analyses. Furthermore, we evaluated the association between LE8 and all-cause mortality in COPD patients using a weighted Cox regression analysis.
resultsWeighted logistic regression analysis of the fully adjusted model indicated that a higher LE8 score was associated with a lower prevalence of COPD (OR = 0.75; 95% CI, 0.71-0.79). The RCS curves showed a linear negative association between them. LE8 score was negatively correlated with the prevalence of COPD across all subgroups, and this negative correlation was significant in those younger than 60 years old. The sensitivity analysis's results were consistent with the primary findings. Furthermore, weighted Cox regression analysis of the fully adjusted model showed that LE8 score was negatively associated with all-cause mortality in COPD patients (HR = 0.81, 95% CI = 0.74-0.89).
conclusionsLE8 score was negatively associated not only with the prevalence of COPD, but also with all-cause mortality in patients with COPD. CLINICAL TRIAL NUMBER: Not applicable.
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