ArticleBMC infectious diseases2025
Infective aortitis caused by Corynebacterium striatum in a patient with twice orthotopic heart transplantation.
Article in BMC infectious diseases, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundInfective aortitis (IA) with vegetation formation is a rare but potentially life-threatening complication in patients with heart transplantation (HTx). IA caused by Corynebacterium striatum (C. striatum) has scarcely been reported. Herein, we present a case of IA caused by C. striatum in a young man eight months after his second orthotopic HTx. CASE PRESENTATION: We present a case of IA caused by C. striatum in a young man eight months after his second orthotopic HTx. The clinical course was complicated by recurrent fever, persistent bacteremia, anemia, and multiple peripheral arterial embolisms. While transthoracic echocardiography (TTE) revealed normal cardiac valves and endocardium, transesophageal echocardiography (TEE) confirmed an intraluminal mass in the anastomotic site of ascending aortic. The patient declined surgical intervention but responded well to medical therapy. He got resolution of infection following 6 weeks of vancomycin and remained well upon 34 months of follow-up without recurrent fever or new embolic events.
conclusionsThis case highlights the importance of evaluating the anastomotic site of ascending aortic in the context of bacteremia for HTx recipients, especially when routine TTE shows no valvular or endocardial involvement.
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