ArticleInternational journal of emergency medicine2025
The association between the severity of out-of-hospital cardiac arrest and the effectiveness of target temperature management: a retrospective study based on prediction models.
Article in International journal of emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
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9 authors.
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Abstract
aimThis study aimed to develop prediction models and conduct risk stratifications for patients with out-of-hospital cardiac arrest (OHCA) to identify patients who could benefit from targeted temperature management (TTM) at 33°C.
methodsA retrospective analysis was carried out on 368 patients and the primary outcome was the neurological outcome at discharge evaluated by the Cerebral Performance Categories (CPC) scale. Six variables were utilized to construct prediction models via six methodologies, and the Chi-square test or Fisher's exact test was used to analyze the efficacy of TTM at 33℃ under diverse risk stratifications.
resultsA total of 264 eligible patients were divided into the development cohort and test set. The identified predictors comprised bystander cardiopulmonary resuscitation (CPR), pupillary light reflex, Acute Physiology and Chronic Health Evaluation II (APACHE II) score, lactate, serum calcium (Ca
conclusionPrediction models developed from early variables can predict the neurological prognosis of OHCA, and the efficacy of 33℃ TTM may be related to severity.
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