Evidence map›Paper›PMID 40830927›Full record

ArticleBMC plant biology2025

Histone ZmH2B regulates resistance to the Southern corn leaf blight pathogen Bipolaris maydis in maize.

Ying Ding, Hongliang Wu, Na Ning, Haiyue Yu, Chaotian Liu, Ruoya Lv, Shu Li, Junjie Hao, Xintao Wang, Xuecai Zhang and 4 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC plant biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Ying Ding *College of Plant Protection, Shanxi Agricultural University, Taigu, 030801, China.
Hongliang Wu *State Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Na NingState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Haiyue YuState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Chaotian LiuState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Ruoya LvState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Shu LiState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China.
Junjie HaoInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China.
Xintao WangInstitute of Plant Protection, Henan Academy of Agricultural Sciences, Zhengzhou, 450002, China.
Xuecai ZhangInternational Maize and Wheat Improvement Center (CIMMYT), 56237, Texcoco, Mexico.
Xin XieCollege of Agriculture, Guizhou University, Guiyang, 550025, China.
Xinfeng LiCollege of Plant Protection, Shanxi Agricultural University, Taigu, 030801, China.
Wende LiuState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China. liuwende@caas.cn.
Zhiqiang LiState Key Laboratory for Biology of Plant Diseases and Insect Pests, Institute of Plant Protection, Chinese Academy of Agricultural Sciences, Beijing, 100193, China. lizhiqiang05@caas.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundH2B histones play crucial roles in plant responses to biotic stress. However, to date, most research on H2B histones has focused on their roles in post-translational modification, and studies specifically investigating the intrinsic properties of these histones remain relatively limited. Here we identified the ZmH2B in maize (Zea mays) and investigated its role in the response of maize to infection by the Southern corn leaf blight pathogen Bipolaris maydis.

resultIn this study, a nucleus-localized ZmH2B was identified from maize. To characterize the role of this histone in disease resistance, we employed virus-induced gene silencing (VIGS) and transient overexpression (VOX) to generate ZmH2B-silenced (FoMV:ZmH2B) and ZmH2B-overexpressing (FoMV:ZmH2B-VOX) lines. FoMV:ZmH2B lines showed enhanced B. maydis infection and an inhibited chitin-induced reactive oxygen species burst, whereas FoMV:ZmH2B-VOX lines exhibited the opposite effects. Furthermore, ZmH2B overexpression induced the expression of various pathogenesis-related genes, suggesting that these genes enhance resistance against B. maydis. Transcriptome analysis of ZmH2B-silenced plants revealed that the differentially expressed genes were predominantly enriched in photosynthesis-related pathways, pointing to a role for photosynthesis in B. maydis resistance.

conclusionsThese results suggest that ZmH2B positively regulates maize resistance to B. maydis.

Indexed as

BipolarisDisease ResistanceHistonesPlant DiseasesPlant ProteinsZea maysGene Expression Regulation, PlantGene SilencingPlant LeavesHistonesPlant ProteinsBipolaris maydisMaizeTranscriptome analysisVirus-induced gene silencing and overexpressionZmH2B

Identifiers

PMID40830927
PMCPMC12362849

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