Evidence map›Paper›PMID 40830923›Full record

ArticleCommunity dentistry and oral epidemiology2025

Oral and Oropharyngeal Cancer Mortality in Brazil: Estimates and Projections up to 2042.

Luiz Alexandre Chisini, Luana Carla Salvi, Francine Dos Santos Costa, Rodrigo Varella de Carvalho, Ana Carolina Uchoa Vasconcelos

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Article in Community dentistry and oral epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Luiz Alexandre ChisiniDepartment of Restorative Dentistry, School of Dentistry, Federal University of Pelotas, Pelotas, Rio Grande do Sul, Brazil.ORCID 0000-0002-3695-0361
Luana Carla SalviRadboudUMC, Nijmegen, the Netherlands.ORCID 0000-0001-5809-8272
Francine Dos Santos CostaFederal University Pelotas, Pelotas, Rio Grande do Sul, Brazil.
Rodrigo Varella de CarvalhoDepartment of Dentristry, Federal University of Juiz de Fora, Governador Valadares, Minas Gerais, Brazil.
Ana Carolina Uchoa VasconcelosSchool of Dentistry, Faculty of Pharmacy, Dentistry and Nursing, Federal University of Ceará, Fortaleza, Brazil.ORCID 0000-0001-6560-9536

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess the effect of age-period-birth cohort on mortality rates related to lip/oral and oropharyngeal cancer (LOOPC) in Brazil from 1980 to 2019 and to estimate the future mortality rate for 2042. MATERIALS AND

methodsMortality rate per 100 000 inhabitants, and age-standardised mortality rate (ASR) per 100 000 inhabitants were estimated. The Prais-Winsten regression model was used to estimate the trends and the annual percent change (APC%). The age-period-cohort effects were calculated using the Poisson regression model. Lee-Carter model was employed to perform projections.

resultsA total of 134 941 deaths were observed. Prais-Winsten regression model revealed a slight upward trend in lip and oral cancer mortality among men (p = 0.04) and women (p = 0.02), as well as in oropharyngeal cancer among men (p = 0.02). Significant age-period-cohort was observed for LOOPC in both sexes (p < 0.01). The risk ratio declined in recent cohorts for men (Both Cancers) but increased for women (Lip/Oral Cancer). Period analysis showed a risk increase for lip/oral cancer in recent periods in both sexes and a decrease for men and women for oropharyngeal cancer. In 2042, mortality projections decrease in lip/oral cancer for men aged between 40 and 60 years and oropharyngeal cancer in men between 35 and 60 years. For women, no significant changes are projected. The model projections mortality rate reveal varied outcomes across the diverse regions of Brazil.

conclusionA significant age-period cohort was observed over the 40 years assessed. Projections for 2042 indicated a significant decrease in LOOPC mortality rates for men and no change for women.

Indexed as

Mouth NeoplasmsOropharyngeal NeoplasmsAdultAgedAged, 80 and overBrazilFemaleForecastingHumansMaleMiddle AgedMortalityYoung Adultepidemiologymortalitiesmortality ratesmouth neoplasmoral neoplasm

Identifiers

PMID40830923
PMCPMC12627273

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.