Evidence map›Paper›PMID 40830896›Full record

ArticleEuropean journal of medical research2025

Development and validation of a nomogram for in-hospital mortality prediction in acute myocardialinfarction patients with cardiac arrest undergoing percutaneous coronary intervention supported by veno-arterial extracorporeal membrane oxygenation.

Haina Li, Mingxuan Duan, Guoyu Duan, Yan Zhou, Xiaoyan Zhao

Abstract readValidation Study
In one paragraph

Article in European journal of medical research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Haina LiDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Mingxuan DuanDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Guoyu DuanDepartment of Emergency Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Yan ZhouDepartment of Emergency Medicine, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China.
Xiaoyan ZhaoDepartment of Cardiology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou, 450052, China. fcczhaoxy8@zzu.edu.cn.

Funding

the Education Department of Henan Province 24A320085
6 · The paper itself

Abstract

backgroundThe combination of percutaneous coronary intervention (PCI) and veno-arterial extracorporeal membrane oxygenation (VA-ECMO) has become a widely used approach for resuscitating patients with acute myocardial infarction (AMI) complicated by cardiac arrest (CA). Nonetheless, limited research has focused on predicting in-hospital mortality in affected patients. This study aims to identify factors associated with in-hospital mortality and develop a clinical prediction model for these patients.

methodsClinical presentations of AMI patients with CA undergoing PCI supported by VA-ECMO at two hospitals in Zhengzhou were evaluated. Patients were stratified based on their survival status at discharge. A comprehensive analysis, which included univariate logistic regression, LASSO regression, and multivariate logistic regression, was conducted to identify predictors and develop a nomogram for in-hospital mortality. The nomogram's predictive performance was subsequently compared to that of existing models.

resultsThe study included 139 patients, of whom 84 died during hospitalization. Using factors such as age, current smoking, left main culprit vessel, lactic acid levels, and serum creatinine, a nomogram model was developed. The model demonstrated good predictive performance, with an area under the curve of 0.826 (95% CI 0.757-0.894) in the training dataset and 0.783 (95% CI 0.706-0.859) in the internal validation dataset, indicating high accuracy and stability. Clinical decision curve analysis confirmed the model's utility, particularly for risk thresholds above 20%, outperforming existing models.

conclusionsThis study identified independent predictors of in-hospital mortality in AMI patients with CA undergoing PCI supported by VA-ECMO and developed a clinically applicable prediction model.

Indexed as

Extracorporeal Membrane OxygenationHeart ArrestHospital MortalityMyocardial InfarctionNomogramsPercutaneous Coronary InterventionAgedFemaleHumansMaleMiddle AgedRetrospective StudiesAcute myocardial infarctionCardiac arrestIn-hospital mortalityNomogramVeno-arterial extracorporeal membrane oxygenation

Identifiers

PMID40830896
PMCPMC12363090

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.