ArticleBMC gastroenterology2025
Insights from age-stratified endoscopic detection metrics support initiating colorectal cancer screening at age 45.
Article in BMC gastroenterology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
4 citing papers in PubMed.
- The COMPLETE-CRC Screening Initiative: Increasing Colonoscopy Completion After Positive Stool-Based Colorectal Cancer Screening.Digestive diseases and sciences · 2026Article
- Factors Associated with Ever Undergoing Colorectal Cancer Testing Among Adults in the United States.Diseases (Basel, Switzerland) · 2026Article
- Fecal Immunochemical Test and Multitarget Stool DNA Testing for Colorectal Cancer Screening in Real-World Practice: A Literature Review.Journal of clinical medicine · 2026Review
- Comparative analysis of bowel preparation quality for colonoscopy: a survey of outpatients and inpatients.BMC gastroenterology · 2026Article
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
aimAll major U.S. guidelines now validate average-risk colorectal cancer (CRC) screening at 45-49 years of age. We aimed to highlight the importance of promoting colonoscopy among younger populations as part of a comprehensive strategy to reduce the burden of CRC.
methodsOur study analyzed data from 235,782 colonoscopy reports of individuals, which were categorized into six age groups: 45-49 years, 50-54 years, 55-59 years, 60-64 years, 65-69 years, and 70-74 years. Parameters such as age, gender, histopathology of polyps, quantity of polyps, and polyp detection rate (PDR) were assessed.
resultsOur study shows a progressive increase in colonoscopy uptake among individuals aged 45-54. PDR increased significantly with age, from 25.7% in the 45-49 group to 40.2% in the 70-74 group (p < 0.05). Notably, the PDR difference between the 45-49 and 50-54 groups was not statistically significant (25.7% vs. 26.8%, p = ns), indicating comparable polyp burden. Carcinoma detection rates followed a similar pattern, with no significant difference between the 45-49 (0.29%) and 50-54 (0.29%) groups, while a substantial rise occurred from age 55 onwards (p < 0.05).
conclusionsIndividuals screened in the 45-49 age group exhibited comparable PDR and carcinoma detection rates to those in the 50-54 age range.
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