ArticleBMC geriatrics2025
Appetite loss in older adults without undernutrition: associated factors and clinical implications.
Article in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Malnutrition, diet quality, and psychological well-being in older adults: a hospital outpatient study.BMC geriatrics · 2026Article
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7 authors.
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No grant is acknowledged in the PubMed record.
Abstract
backgroundThe aim of this study was to investigate the clinical implications of appetite loss in older adults with normal nutritional status, prior to the development of malnutrition.
methodsThis study included a total of 755 older outpatients with normal nutritional status as determined by the Mini Nutritional Assessment (MNA ≥ 24). Council on Nutrition Appetite Questionnaire was used to assess appetite status. Patients with a CNAQ score of ≤ 28/40 were identified as having a reduced appetite. Sociodemographic characteristics, anthropometric measurements, comorbidities, number of drugs, and laboratory data at the time of outpatient clinic admission were recorded. A comprehensive geriatric assessment was performed for all patients.
resultsThe mean age was 78.6 ± 7.7 years, and 66.8% were female. A total of 192 patients (25.4%) were identified with appetite loss. Individuals with appetite loss were older, more likely to be female, and more likely to have chronic kidney disease than those without appetite loss were (p < 0.05), while their educational level was lower. In the multivariate logistic regression, after adjusting for age, sex, years of education, and chronic kidney disease, there was an association between lower Tinetti Balance and Gait Scale scores, higher Geriatric Depression Scale-15 scores, and the number of medications associated with appetite loss (p < 0.05).
conclusionsAppetite loss was observed in one out of four older adults with normal nutritional status (MNA ≥ 24). Appetite loss was associated with advanced age, female sex, lower educational level, chronic kidney disease, and polypharmacy. Older patients with appetite loss had more balance and gait disturbances and depressive symptoms even if they were well nourished.
trial registrationNot applicable. This study is observational and not a clinical trial.
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