ArticleBMC cardiovascular disorders2025
Prognostic value of systemic immune-Inflammatory index in patients with diabetes mellitus and acute coronary syndrome after percutaneous coronary intervention: a prospective cohort study.
Article in BMC cardiovascular disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
6 citing papers in PubMed.
- The predictive value of the systemic immune-inflammation index in chronic thromboembolic pulmonary hypertension.Medicine · 2026Article
- Distinguishing myocarditis from perimyocardial syndromes in children presenting to the emergency department: a biomarker-based approach.BMC emergency medicine · 2026Article
- Interpretable machine learning for predicting in-hospital bleeding after PCI in patients with diabetes and acute coronary syndrome: a retrospective cohort study.BMC cardiovascular disorders · 2026Article
- Systemic Immune-Inflammation Index is Associated with Pressure Injury in Hospitalized Patients with Non-Small Cell Lung Cancer: A Retrospective Cohort Study.Cancer management and research · 2026Article
- The Systemic Immune-Inflammation Index as a Predictor of Clinical Outcomes in Chronic Coronary Syndrome: Influence of Diabetes Mellitus.Journal of inflammation research · 2026Article
- The association between systemic immune-inflammation index and mortality of elderly chronic bronchitis patients complicated by acute myocardial infarction.Frontiers in cardiovascular medicine · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
Abstract
backgroundA higher risk of cardiovascular disease has been correlated with several inflammatory biomarkers, one of which is the systemic immune-inflammatory index (SII). Nevertheless, the relationship between SII and major adverse cardiovascular and cerebrovascular events (MACCE) in patients with diabetes and acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI) remains unclear. The objective of this study was to assess the prognostic value of SII for the risk of MACCE in patients with diabetes and ACS who underwent PCI.
methodsThis study included 1782 patients with ACS and diabetes who underwent PCI successfully at Beijing Anzhen Hospital between August 2021 and April 2022, with a median follow-up of 16.2 months. According to the optimal SII cut-off value for MACCE, patients were categorized into two groups: the high SII group (SII ≥ 735.82 × 10
resultsThe incidence of MACCE was significantly higher in the high SII group than in the low SII group (11.3% vs. 6.7%, log-rank P < 0.001), indicating that among 22 patients with high SII levels, an additional MACCE event is expected to occur. Univariate Cox proportional hazards models showed that higher SII was associated with an increased incidence of MACCE (HR: 1.739, 95%CI: 1.254-2.410). After full adjustment, higher SII remained an independent risk factor for MACCE (HR: 1.540, 95%CI: 1.098-2.160) and unplanned revascularization (HR: 1.526, 95%CI: 1.011-2.301).
conclusionThis study found that elevated SII is an independent risk factor for predicting MACCE in patients with ACS and diabetes mellitus after PCI, providing a theoretical basis for postoperative anti-inflammatory therapy in this population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.