ArticleBMC emergency medicine2025
Moderate and severe traumatic brain injury: abbreviated injury scale scoring and coding of traumatic axonal injury from early MRI.
Article in BMC emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
backgroundIn this large prospective study of patients with moderate and severe traumatic brain injury (TBI) examined with early magnetic resonance imaging (MRI), we aimed to explore the differences in the occurrence and degree of traumatic axonal injury (TAI) reported on early MRI compared with (1) the original Abbreviated Injury Scale (AIS)-TAI coding and (2) a pragmatic AIS-TAI coding approach. The latter approach also allowed the assignment of TAI codes to patients with short periods of coma, sedated patients and patients with concurrent mass lesions, which are exclusion criteria in the original AIS-TAI scoring.
methodsA total of 311 patients with moderate (n=156) or severe (n=155) TBI, aged 8–70 years, admitted to a regional Level 1 trauma center and examined with early head MRI within six weeks (median 9 days) were included. Consultants in radiology reported TAI and TAI grades using the MRI sequences fluid-attenuated inversion recovery, diffusion-weighted imaging and either T2* gradient echo or susceptibility-weighted imaging. The AIS head score was reported according to the original AIS-TAI coding and using a pragmatic AIS-TAI coding approach.
resultsOf all patients, 80% (n=249) had TAI lesions on early MRI. Using the original AIS-TAI criteria, only four patients (1%) were eligible to receive a TAI code, and they all had TAI grade 1 on early MRI. Using a pragmatic AIS-TAI coding approach, 50% (125/249) of the patients with TAI on MRI received a TAI code as part of their AIS head score.
conclusionOur study demonstrates a substantial discrepancy in the proportion of patients diagnosed with TAI as part of the AIS head score, especially when the original AIS-TAI coding criteria were used but also when the pragmatic AIS-TAI coding was used, compared with findings of TAI on early MRI. Hence, we suggest a revision of the TAI coding in the AIS Dictionary, which is more reliant on findings on early MRI, which is increasingly performed in patients with moderate–severe TBI. CLINICAL TRIAL NUMBER: Not applicable.
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