Observational studyBMC emergency medicine2025
Association of lung ultrasound score with 72-hour intubation needs in pneumonia patients presenting to the emergency department.
Observational study in BMC emergency medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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11 authors.
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Abstract
backgroundThe lung ultrasound (LUS) score is a semi-quantitative tool used to predict clinical outcomes in conditions such as congestive heart failure and acute respiratory distress syndrome. However, its role in pneumonia remains unclear. This study aimed to determine whether the LUS score is associated with the need for intubation within 72 h of emergency department (ED) presentation.
methodsThis prospective observational study enrolled adults (≥ 18 years) who were diagnosed with pneumonia in the ED. The LUS score was calculated by summing findings from 12 thoracic regions. We then examined the relationship between the total LUS score and the need for endotracheal intubation (ETI).
resultsForty-five patients were included. The median LUS score was 13.0 (IQR: 5.5‒19.0). Patients who required ETI had a significantly higher median LUS score (19.0, IQR: 17.0‒26.0) compared with those who did not require ETI (12.0, IQR: 4.25‒18.0; P = 0.002). The LUS score demonstrated strong predictive ability for ETI, with an area under the receiver operating characteristic curve of 0.83 (95% CI: 0.71‒0.95). The optimal cutoff value of 16 yielded a sensitivity of 88.9%, specificity of 69.4%, positive predictive value of 42.1%, and negative predictive value of 96.2%. Higher LUS scores were significantly associated with increased 28-day mortality (P = 0.04).
conclusionsAmong patients with pneumonia presenting to the ED, the LUS score was associated with the need for ETI and was linked to higher 28-day mortality.
trial registrationThis study was registered in Thai clinical trial registry (TCTR20230518003) on May 18, 2023.
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