Evidence map›Paper›PMID 40830418›Full record

ArticleMikrochimica acta2025

Copper single-atom-based flexible aptamer biochip for simultaneous monitoring of bladder cancer-related bacteria.

Jiayue Sun, Hongbin Yang, Junlong Zhuang, Ran Chen, Yu Zhang, Kangling Tian, Longwang Lei, Yuxuan Yang, Chang Ming Li, Fangxin Hu

Abstract read
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Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jiayue SunCollege of Life Science, Qingdao University, Qingdao, 266071, People's Republic of China.
Hongbin YangSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, People's Republic of China.
Junlong ZhuangDepartment of Urology, Affiliated Hospital of Medical School, Nanjing Drum Tower Hospital, Nanjing University, Nanjing, People's Republic of China.
Ran ChenSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, People's Republic of China.
Yu ZhangSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, People's Republic of China.
Kangling TianSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, People's Republic of China.
Longwang LeiSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, People's Republic of China.
Yuxuan YangSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, People's Republic of China.
Chang Ming LiSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, People's Republic of China. ecmli@usts.edu.cn.
Fangxin HuSchool of Materials Science and Engineering, Suzhou University of Science and Technology, Suzhou, 215009, People's Republic of China. hufx278@usts.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

R apid and accurate detection of pathogenic bacteria is crucial for disease diagnosis in clinical practice. The infection of Escherichia coli (E. coli) and Staphylococcus aureus (S. aureus) is closely related to the development and complications of patients with bladder cancer. In this study, an aptamer biochip for E. coli and S. aureus simultaneous detection was developed based on copper single atom material (Cu-SAC) and gold nanoparticles (AuNPs) via high-resolution electrohydrodynamic (EHD) printing technology. The main strategy was based on the specific recognition of aptamer and the signal amplification of AuNPs/Cu-SAC. Following aptamer immobilization, the electrochemical signal gradually decreased. Using this proposed electrochemical aptamer biochip, E. coli and S. aureus can be quantified at a linearity range of 10-1.0 × 10

Indexed as

Aptamers, NucleotideBiosensing TechniquesCopperEscherichia coliStaphylococcus aureusUrinary Bladder NeoplasmsAnimalsElectrochemical TechniquesGoldHumansLimit of DetectionMetal NanoparticlesMilkAptamers, NucleotideCopperGoldAptamer biochipCopper single atom materialEscherichia coliPathogenic bacteria detectionStaphylococcus aureus

Identifiers

PMID40830418

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.