Evidence map›Paper›PMID 40830343›Full record

ReviewCell death & disease2025

Biogenesis, functional roles, and pathological implications of migrasomes.

Xuexue Liu, Dun Liu, Heng Zhao, Kangxue Wu, Shaoping Yin, Xian Yang, Chuanqin Chen, Xiaolong Ma, Yonghuan Mao, Haixia Zhang and 3 more

Abstract readReview
In one paragraph

Review in Cell death & disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Integrating computational engines to identifyFrontiers in immunology · 2026
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Xuexue Liu *Department of Pharmacy, Nanjing Medical Center for Clinical Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Dun Liu *Division of Spine Surgery, Department of Orthopedic Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Heng Zhao *Department of Endocrinology, Jinling Hospital, Medical School of Nanjing University, Nanjing, China.
Kangxue WuDepartment of Pharmacy, Nanjing Medical Center for Clinical Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. 1270068879@qq.com.ORCID http://orcid.org/0009-0006-6511-3243
Shaoping YinSchool of Pharmacy, Nanjing University of Chinese Medicine, Nanjing, China.
Xian YangDepartment of Pharmacy, Nanjing Medical Center for Clinical Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Chuanqin ChenDepartment of Colorectal Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Xiaolong MaDepartment of Colorectal Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Yonghuan MaoDepartment of Colorectal Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Haixia ZhangDepartment of Pharmacy, Nanjing Medical Center for Clinical Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Lihua ShaoDepartment of Colorectal Surgery, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. digua0024@126.com.ORCID http://orcid.org/0000-0002-9605-6994
Siliang WangDepartment of Pharmacy, Nanjing Medical Center for Clinical Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. wsl_dth@126.com.ORCID http://orcid.org/0000-0003-1228-869X
Xiao DuDepartment of Pharmacy, Nanjing Medical Center for Clinical Pharmacy, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China. duxiaojianai@126.com.ORCID http://orcid.org/0000-0001-5398-4515

Funding

China Postdoctoral Science Foundation 2024M761411
6 · The paper itself

Abstract

Migrasomes are a newly discovered type of organelle, typically located at the tips or intersections of retraction fibers, containing vesicles of various sizes and numbers. During cell migration, migrasomes expand in size, are accompanied by the rupture of retraction fibers, and eventually enter the intercellular space or are absorbed by neighboring cells. Increasing research has shown that migrasomes play crucial roles in cellular growth and development, including maintaining intracellular homeostasis and facilitating intercellular communication. This review focuses on the biogenesis, functions, and pathological roles of migrasomes, while also exploring their future research prospects. As a novel mechanism of intercellular communication, migrasomes hold immense potential for therapeutic applications. A deeper understanding of how to leverage their physiological functions for disease diagnosis and treatment will be a critical focus of future investigations.

Indexed as

Cell MovementAnimalsCell CommunicationHumans

Identifiers

PMID40830343
PMCPMC12365025

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.