Evidence map›Paper›PMID 40830340›Full record

ArticleNature communications2025

Current practices in the study of biomolecular condensates: a community comment.

Simon Alberti, Paolo Arosio, Robert B Best, Steven Boeynaems, Danfeng Cai, Rosana Collepardo-Guevara, Gregory L Dignon, Rumiana Dimova, Shana Elbaum-Garfinkle, Nicolas L Fawzi and 24 more

Abstract read
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Review
  6. Review
  7. Article
  8. Review
  9. Review
  10. Redox-Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  11. A Unifying Thermodynamic Model for Phase Separation and Aging of Biopolymers.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. ACS omega · 2026
    Article
  18. Article
  19. Article
  20. Sketching microprotein portraits.Protein science : a publication of the Protein Society · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

34 authors.

Simon AlbertiBiotechnology Center, Technische Universität Dresden, Dresden, Germany. simon.alberti@tu-dresden.de.ORCID http://orcid.org/0000-0003-4017-6505
Paolo ArosioDepartment of Chemistry and Applied Biosciences, ETH Zurich, Zurich, Switzerland.ORCID http://orcid.org/0000-0002-2740-1205
Robert B BestLaboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, USA.ORCID http://orcid.org/0000-0002-7893-3543
Steven BoeynaemsDepartment of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX, USA.ORCID http://orcid.org/0000-0002-9705-9871
Danfeng CaiDepartment of Biochemistry and Molecular Biology, Johns Hopkins Bloomberg School of Public Health, Baltimore, USA.ORCID http://orcid.org/0000-0003-1623-5077
Rosana Collepardo-GuevaraYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK. rc597@cam.ac.uk.
Gregory L DignonDepartment of Chemical and Biochemical Engineering, Rutgers, State University of New Jersey, Piscataway, USA.
Rumiana DimovaMax Planck Institute of Colloids and Interfaces, Potsdam, Germany.ORCID http://orcid.org/0000-0002-3872-8502
Shana Elbaum-GarfinkleStructural Biology Initiative, Advanced Science Research Center, CUNY, New York, NY, USA.ORCID http://orcid.org/0000-0002-3953-7329
Nicolas L FawziDepartment of Molecular Biology, Cell Biology, and Biochemistry, Brown University, Providence, RI, USA.ORCID http://orcid.org/0000-0001-5483-0577
Monika FuxreiterDepartment of Biomedical Sciences, University of Padova, Padova, Italy.ORCID http://orcid.org/0000-0002-4463-6727
Amy S GladfelterDepartment of Cell Biology, Duke University, Durham, USA. amy.gladfelter@duke.edu.ORCID http://orcid.org/0000-0002-2490-6945
Alf HonigmannTechnische Universität Dresden, Center for Molecular and Cellular Bioengineering (CMCB), Dresden, Germany.ORCID http://orcid.org/0000-0003-0475-3790
Ankur JainWhitehead Institute for Biomedical Research, 455 Main Street, Cambridge, MA, USA.ORCID http://orcid.org/0000-0002-0917-1602
Jerelle A JosephDepartment of Chemical and Biological Engineering, Omenn-Darling Bioengineering Institute, Princeton University, Princeton, NJ, USA.ORCID http://orcid.org/0000-0003-4525-180X
Tuomas P J KnowlesYusuf Hamied Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.ORCID http://orcid.org/0000-0002-7879-0140
Keren LaskerDepartment of Integrative Structural & Computational Biology, The Scripps Research Institute, La Jolla, CA, USA.ORCID http://orcid.org/0000-0002-5480-4173
Edward A LemkeBiocenter, Johannes Gutenberg University Mainz, 55128, Mainz, Germany.ORCID http://orcid.org/0000-0002-0634-0503
Kresten Lindorff-LarsenLinderstrøm-Lang Centre for Protein Science, Department of Biology, University of Copenhagen, Copenhagen, Denmark.ORCID http://orcid.org/0000-0002-4750-6039
Reinhard LipowskyMax Planck Institute of Colloids and Interfaces, Potsdam, Germany.ORCID http://orcid.org/0000-0001-8417-8567
Jeetain MittalArtie McFerrin Department of Chemical Engineering, Texas A&M University, College Station, TX, USA. jeetain@tamu.edu.ORCID http://orcid.org/0000-0002-9725-6402
Samrat MukhopadhyayDepartment of Biological Sciences, Indian Institute of Science Education and Research (IISER), Mohali, India.ORCID http://orcid.org/0000-0003-1242-9958
Sua MyongProgram for Cellular Molecular Medicine (PCMM), Pediatrics Department, Boston Children's Hospital, Boston, USA. sua.myong@childrens.harvard.edu.ORCID http://orcid.org/0000-0001-9098-3423
Rohit V PappuDepartment of Biomedical Engineering and Center for Biomolecular Condensates, James F. McKelvey School of Engineering, Washington University in St. Louis, St. Louis, MO, USA.ORCID http://orcid.org/0000-0003-2568-1378
Karsten RippeGerman Cancer Research Center (DKFZ) Heidelberg, Division of Chromatin Networks, Heidelberg, Germany.ORCID http://orcid.org/0000-0001-9951-9395
Tatyana A ShelkovnikovaSheffield Institute for Translational Neuroscience (SITraN), University of Sheffield, Sheffield, United Kingdom.ORCID http://orcid.org/0000-0003-1367-5309
Anthony G VecchiarelliDepartment of Molecular, Cellular, and Developmental Biology, University of Michigan, Ann Arbor, MI, USA.ORCID http://orcid.org/0000-0002-6198-3245
Susanne WegmannGerman Center for Neurodegenerative Diseases (DZNE), Charitéplatz 1, 10117, Berlin, Germany.ORCID http://orcid.org/0000-0002-5388-2479
Huaiying ZhangDepartment of Biological Sciences, Carnegie Mellon University, Pittsburgh, USA.ORCID http://orcid.org/0000-0002-1784-2664
Mingjie ZhangSchool of Life Sciences, Southern University of Science and Technology, Shenzhen, Guangdong, China.ORCID http://orcid.org/0000-0001-9404-0190
Chloe ZubietaLaboratoire de Physiologie Cellulaire et Végétale, Commissariat à l'énergie atomique et aux énergies alternatives (CEA), 17 ave. des Martyrs, 38000, Grenoble, France.ORCID http://orcid.org/0000-0003-4558-9333
Markus ZweckstetterDepartment for NMR-based Structural Biology, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany. markus.zweckstetter@dzne.de.ORCID http://orcid.org/0000-0002-2536-6581
Dorothee DormannBiocenter, Johannes Gutenberg University Mainz, 55128, Mainz, Germany. ddormann@uni-mainz.de.ORCID http://orcid.org/0000-0002-9260-2775
Tanja MittagDepartment of Structural Biology, St. Jude Children's Research Hospital, Memphis, TN, USA. tanja.mittag@stjude.org.ORCID http://orcid.org/0000-0002-1827-3811

Funding

Understanding the Sequence and Structural Determinants of Phase Behavior of ALS-Causing ProteinsR01NS121114 · NINDS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI Tanja Mittag, ROHIT V PAPPU · 2021 to 2026
$3.8M
Functional and Pathological Interactions of TDP-43R01NS116176 · NINDS · BROWN UNIVERSITY · PI FAWZI, NICOLAS LUX, MITTAL, JEETAIN · 2020 to 2024
$3.6M
Defining the Role of Poly ADP-ribose in Biomolecular Condensation in ALS and FTLDRF1AG071326 · NIA · JOHNS HOPKINS UNIVERSITY · PI LEUNG, ANTHONY K L, MYONG, SUA · 2020 to 2020
$2.6M
Probing the Formation and Function of Transcription Hubs-Equipment SupplementR35GM142837 · NIGMS · JOHNS HOPKINS UNIVERSITY · PI CAI, DANFENG · 2021 to 2025
$2.4M
Molecular Assembly and Disassembly of RNA-Protein Complexes Implicated in ALS/FTDRF1NS113636 · NINDS · JOHNS HOPKINS UNIVERSITY · PI MYONG, SUA · 2019 to 2019
$2.0M
Residue-by-residue details of FUS protein phase separation and aggregationR01GM147677 · NIGMS · BROWN UNIVERSITY · PI FAWZI, NICOLAS LUX · 2022 to 2025
$1.7M
Dissecting the contributions of phase separation to yeast transcription .R01GM154414 · NIGMS · ST. JUDE CHILDREN'S RESEARCH HOSPITAL · PI ASEEM Z ANSARI, Tanja Mittag · 2024 to 2026
$1.5M
Physical laws to control and regulate composition of multi-component biomolecular condensatesR35GM150589 · NIGMS · RUTGERS, THE STATE UNIV OF N.J. · PI Gregory Dignon · 2023 to 2026
$1.4M
Uncovering the role of extracellular condensates as triggers of neuroinflammationDP2NS142714 · NINDS · BAYLOR COLLEGE OF MEDICINE · PI BOEYNAEMS, STEVEN · 2024 to 2024
$1.4M
Liquid-Liquid Phase Separation in Heterochromatin OrganizationR01GM136917 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI MITTAL, JEETAIN · 2020 to 2023
$1.4M
Multiscale Computational Models to Investigate the Role of Phase Separation in BiologyR35GM153388 · NIGMS · TEXAS ENGINEERING EXPERIMENT STATION · PI Jeetain Mittal · 2024 to 2026
$1.3M
Inside Condensates: Bridging molecular structure and condensate material properties through simulationR35GM155259 · NIGMS · PRINCETON UNIVERSITY · PI Jerelle Aurelia Joseph · 2024 to 2026
$1.2M
NIA NIH HHS RF1 AG071326NIGMS NIH HHS R01 GM136917NIGMS NIH HHS R01 GM147677NIGMS NIH HHS R01 GM154414NIGMS NIH HHS R35 GM142837NIGMS NIH HHS R35 GM150589NIGMS NIH HHS R35 GM153388NIGMS NIH HHS R35 GM155259NIGMS NIH HHS R35 GM156800NINDS NIH HHS DP2 NS142714NINDS NIH HHS R01 NS116176NINDS NIH HHS R01 NS121114NINDS NIH HHS R01 NS138605NINDS NIH HHS RF1 NS113636
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Identifiers

PMID40830340
PMCPMC12365244

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