Evidence map›Paper›PMID 40830329›Full record

ReviewDermatology and therapy2025

Cocaine-Induced Dermatomucositis: Clarifying Diagnostic Controversies and Introducing IgG4 Positivity as a New Histopathological Feature.

Francisco Reyes Albaladejo, Miguel Mansilla-Polo, Rafael Botella-Estrada

Abstract readReview
In one paragraph

Review in Dermatology and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Francisco Reyes AlbaladejoUniversidad de Valencia, Valencia, Spain.
Miguel Mansilla-PoloDepartamento de Dermatología. Hospital, Universitario y Politécnico La Fe, Avenida Fernando Abril Martorell 106, CP 46026, Valencia, Spain. miguel_yecla96@hotmail.com.ORCID http://orcid.org/0000-0001-6730-6723
Rafael Botella-EstradaDepartamento de Dermatología. Hospital, Universitario y Politécnico La Fe, Avenida Fernando Abril Martorell 106, CP 46026, Valencia, Spain.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cocaine-induced dermatomucositis is a recently described clinical entity with significant controversy regarding its diagnostic criteria and pathophysiology. While previous reports have identified a distinct pattern of chronic inflammatory mucocutaneous lesions in people who use cocaine, the absence of standardized diagnostic markers has led to inconsistencies in classification. This case series aims to clarify and unify the defining characteristics of cocaine-induced dermatomucositis by analyzing its clinical presentations, histopathologic findings, and immunologic features. Notably, we introduce immunoglobulin G4 (IgG4) positivity as a newly observed characteristic, challenging previous assumptions that excluded IgG4-related immune responses from its pathogenesis. By consolidating clinical and histologic patterns, this study contributes to the ongoing effort to establish cocaine-induced dermatomucositis as a distinct and recognizable disorder, paving the way for improved diagnosis and management.

Indexed as

CocaineDermatomucositisDrug-induced dermatosesIgG4

Identifiers

PMID40830329
PMCPMC12549497

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.