Evidence map›Paper›PMID 40830325›Full record

ReviewNeurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology2025

Unexplained cerebral hemiatrophy in a case of astrocytoma, IDH-Mutant, WHO grade 3: a case report and literature review.

Alice S Juell, Brett J Theeler

Abstract readCase ReportsReview
PubMed Publisher
In one paragraph

Review in Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Alice S JuellNeurology Intern, SAUSHEC Internal Medicine Residency Program, 3551 Roger Brooke Dr, Fort Sam Houston, TX, 78234, USA. alice.s.juell.mil@health.mil.ORCID http://orcid.org/0000-0001-8212-5621
Brett J TheelerDepartment of Neurology, Uniformed Services University of the Health Sciences, Walter Reed National Military Medical Center, 4301 Jones Bridge Rd, Bethesda, MD, 20814, USA.ORCID http://orcid.org/0009-0002-3694-9528

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cerebral hemiatrophy is a known sequela of perinatal insults, autoimmune encephalitides, ischemic stroke, vascular abnormalities, infection, head trauma, and neoplasms. Documented cases of primary brain tumor-associated hemiatrophy have been described mostly in germinoma cases, with only four cases involving astrocytomas. We describe the clinical presentation, imaging, and course of a 30-year-old patient with a left frontal astrocytoma, isocitrate dehydrogenase (IDH) mutant, World Health Organization (WHO) grade 3; the patient initially presented with global aphasia out of proportion to the degree of language cortex involvement, and within two months after tumor resection, began to show imaging findings of cerebral hemiatrophy and crossed cerebellar diaschisis. We review existing cases of cerebral hemiatrophy within the literature and proposed mechanisms of pathology.

Indexed as

AstrocytomaBrain NeoplasmsIsocitrate DehydrogenaseAdultAtrophyHumansMagnetic Resonance ImagingMutationIsocitrate DehydrogenaseAstrocytomaCerebral hemiatrophyCrossed cerebellar diaschisisIsocitrate dehydrogenase mutantMRIPrimary brain tumor

Identifiers

PMID40830325

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.