Evidence map›Paper›PMID 40830276›Full record

ArticleMikrochimica acta2025

Upconversion nanoparticle-FITC conjugate as a fluorescence switching probe for the sensitive detection of Tau: an Alzheimer's disease biomarker.

Merin K Abraham, Geneva Indongo, Greeshma Rajeevan, Arathy B K, Dheyaa Mohammed Dhahir, Sony George

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Article in Mikrochimica acta, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Merin K AbrahamDepartment of Chemistry, School of Physical and Mathematical Science, Research Centre, University of Kerala, Kariavattom Campus, Thiruvananthapuram, 695581, Kerala, India.
Geneva IndongoDepartment of Chemistry, School of Physical and Mathematical Science, Research Centre, University of Kerala, Kariavattom Campus, Thiruvananthapuram, 695581, Kerala, India.
Greeshma RajeevanDepartment of Chemistry, School of Physical and Mathematical Science, Research Centre, University of Kerala, Kariavattom Campus, Thiruvananthapuram, 695581, Kerala, India.
Arathy B KDepartment of Chemistry, School of Physical and Mathematical Science, Research Centre, University of Kerala, Kariavattom Campus, Thiruvananthapuram, 695581, Kerala, India.
Dheyaa Mohammed DhahirDepartment of Chemistry, School of Physical and Mathematical Science, Research Centre, University of Kerala, Kariavattom Campus, Thiruvananthapuram, 695581, Kerala, India.
Sony GeorgeDepartment of Chemistry, School of Physical and Mathematical Science, Research Centre, University of Kerala, Kariavattom Campus, Thiruvananthapuram, 695581, Kerala, India. sonygeorge008@gmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neurodegenerative diseases are characterised by gradual loss of neuronal function and corresponding cognitive decline. Current detection methods include PET and MRI scanning, extraction of CSF fluid proteins which are invasive and painful. Hence, the development of a highly selective, cost effective and minimally invasive method for the detection of tau is clinically significant. In this work, we have fabricated an upconversion nanoparticle-FITC immunoprobe conjugate for the detection of tau from human serum. Initially, a blue-emitting Cit@NaYF

Indexed as

Alzheimer DiseaseFluorescein-5-isothiocyanateFluorescent DyesNanoparticlestau ProteinsAntibodies, MonoclonalBiomarkersFluorescence Resonance Energy TransferHumansLimit of DetectionAntibodies, MonoclonalBiomarkersFluorescein-5-isothiocyanateFluorescent DyesMAPT protein, humantau ProteinsAlzheimer’s diseaseFITCFluorescence detectionFRETTauUpconversion nanoparticle

Identifiers

PMID40830276

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.