ArticleNature plants2025
Large-scale pairing identifies a soybean phytocytokine-receptor module conferring disease resistance.
Article in Nature plants, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
10 citing papers in PubMed.
- Peptide hormones in shaping root system architecture and environmental adaptation: Current advances and translational perspectives.Plant communications · 2026Review
- Small Peptides, Smart Plants: The Emerging Significance of SCOOP Signalling.Plant, cell & environment · 2026Review
- Decoding stress resilience in soybean: Regulatory networks and precision breeding under climate change.Journal of integrative plant biology · 2026Review
- Diverse phytocytokines derived from conserved subtilase scaffolds co-evolved with clustered receptors to confer defence responses in legumes.Nature plants · 2026Article
- Omics-driven plant breeding through phenomics-enviromics crosstalk.Nature communications · 2026Review
- Advances in the roles of SCOOP peptides and the receptor-like kinase MIK2 in plant stress responses.Plant cell reports · 2026Review
- Identification of the NBS-LRR gene family and AkNBS-LRR43 and 100 functional analysis under biotic stress.Plant cell reports · 2026Article
- Processing and release of endogenous immunogenic peptide signals.The Plant journal : for cell and molecular biology · 2026Review
- Review
- From Model to Crop: Roles of Macroautophagy inGenes · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
9 authors.
Funding
Abstract
Plant peptide hormones play essential roles in various physiological processes, including activating defence responses to biotic stress. Membrane-localized pattern recognition receptors (PRRs) typically detect peptide hormones to initiate signalling pathways. Through comprehensive peptide-receptor matching, we identified 63 peptide-receptor pairs in soybeans. Among these, the immunomodulatory phytocytokines GmPEP914 and GmPEP890 trigger robust immune responses that suppress a broad spectrum of pathogen infections, mediated by their identified receptors GmPEP914 and GmPEP890 RECEPTOR1 (GmP98R1) and GmP98R2. Biochemical assays combined with AI-based structural modelling demonstrated that both peptides directly bind GmP98Rs with nanomolar affinity, driven primarily by interactions between the receptors and the C-terminal residue of the peptides. The PEP914-P98R module is conserved across Fabales and Cucurbitales, underscoring its evolutionary importance. Collectively, our study establishes a scalable pipeline for systematic peptide-receptor discovery and elucidates the pivotal role of the PEP914-P98R module in soybean disease resistance.
Indexed as
Identifiers
40830272What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.