Evidence map›Paper›PMID 40830238›Full record

ArticleNpj viruses2025

Genomic surveillance in Morocco tracks SARS-CoV-2 variant shift from Alpha to Omicron sublineage JN1.

Oumaima Bouddahab, Safaa Aqillouch, Hicham Charoute, Rachid Noureddine, Adil El Hamouchi, Oumaima Laazaazia, Achraf Aainouss, Hanâ Baba, Ahd Ouladlahsen, Pascal Pineau and 5 more

Abstract read
In one paragraph

Article in Npj viruses, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Oumaima BouddahabVirology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.
Safaa AqillouchVirology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.
Hicham CharouteResearch unit of epidemiology, biostatistics and bioinformatics, Institut Pasteur du Maroc, Casablanca, Morocco.
Rachid NoureddineLaboratoire Morizgo d'analyses médicales, Casablanca, Morocco.
Adil El HamouchiCentre de séquençage génomique, Institut Pasteur du Maroc, Casablanca, Morocco.
Oumaima LaazaaziaVirology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.
Achraf AainoussLaboratoire Morizgo d'analyses médicales, Casablanca, Morocco.
Hanâ BabaBiotechnology R&D Unit, Institut Pasteur du Maroc, Casablanca, Morocco.
Ahd OuladlahsenService des maladies Infectieuses, CHU Ibn Rochd, Casablanca, Morocco.
Pascal PineauInstitut Pasteur, Université Paris Cité, Unité "Organisation Nucléaire et Oncogenèse", Paris, France.
M'hammed SarihService de Parasitologie et des Maladies Vectorielles, Institut Pasteur du Maroc, Casablanca, Morocco.
Abderrahmane MaaroufiVirology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco.
Mustapha LkhiderLaboratory of Virology, Microbiology, Quality and Biotechnology/Ecotoxicology and Biodiversity, Faculty of Sciences and Techniques of Mohammedia, Hassan II University of Casablanca, Casablanca, Morocco.
Abdelhamid BarakatCentre de séquençage génomique, Institut Pasteur du Maroc, Casablanca, Morocco.
Sayeh EzzikouriVirology Unit, Viral Hepatitis Laboratory, Institut Pasteur du Maroc, Casablanca, Morocco. sayeh.ezzikouri@pasteur.ma.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The persistent evolution of SARS-CoV-2 highlights the crucial role of genomic surveillance in tracking emerging variants and guiding public health interventions. We performed whole-genome sequencing on 235 SARS-CoV-2-positive samples collected across Morocco between 2021 and 2024 to characterize viral evolution and variant dynamics. Our analysis revealed a temporal shift in variant prevalence that paralleled global trends: initial co-circulation of Alpha and Delta variants, followed by complete replacement by Omicron and its sub-lineages in 2022. Phylogenetic reconstruction identified key mutations associated with enhanced immune evasion and transmissibility, demonstrating the virus's adaptive capacity. These findings underscore the critical importance of sustained genomic surveillance for monitoring viral evolution, informing vaccine and therapeutic strategies, and guiding public health responses. Our results advocate for expanded collaborative surveillance networks to proactively address threats from SARS-CoV-2 and other betacoronaviruses.

Identifiers

PMID40830238
PMCPMC12365134

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.