ArticleScientific reports2025
Days alive and out of hospital in patients with wild type transthyretin amyloidosis: cohort study.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01347047 (Institutional Registry of Amyloidosis), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Institutional Registry of Amyloidosis (Hospital Italiano de Buenos Aires)
Who cites it
1 citing paper in PubMed.
- Frailty status, clinical and functional outcomes in cardiac amyloidosis: a systematic review and meta-analysis.EClinicalMedicine · 2026Article
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Authors and funding
7 authors.
Funding
Abstract
While overall survival has been extensively studied in amyloidosis, less attention has been given to patient-centered measures that integrate morbidity and mortality. Days Alive and Out of Hospital (DAOH) is an emerging metric that captures both aspects and has potential utility in the evaluation of disease impact.To describe DAOH in patients with wild-type transthyretin amyloidosis (ATTRwt) and explore factors associated with DAOH.Retrospective cohort study used the Institutional Registry of Amyloidosis database of the Hospital Italiano de Buenos Aires (2015-2023). All patients with ATTRwt amyloidosis enrolled in the registry and affiliated with the health maintenance organization of the hospital were included. DAOH were estimated at 1, 3 and 5 years. Associations between DAOH and risk factors were evaluated.61 cases were included. The median age was 83 years, and 89% were male. Median (IQR) DAOH were 365 (353-365), 998 (553-1094) and 1314 (740-1769) days for 1, 3, and 5 years, respectively. Atrial fibrillation was associated with lower DAOH.DAOH is a simple, reproducible metric. Our findings highlight the importance of considering morbidity, not just mortality, in patients with ATTRwt amyloidosis.
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