Evidence map›Paper›PMID 40829871›Full record

ArticleJournal of clinical pathology2026

Bronchial mucoacinar carcinoma: a newly proposed subtype of mucoepidermoid carcinoma in the bronchus.

Yu Zhang, Rui Liang, Gabriel Christopher Purnell, Lei Yan, Alia Nazarullah, Sarah Hackman, Courtney Thomas, Aaron M Abarbanell, Aaron Sugalski, Jeffrey L Foster and 5 more

Abstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of clinical pathology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Mucoacinar Carcinoma of the Parotid Gland.Head and neck pathology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Yu ZhangDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.ORCID http://orcid.org/0000-0002-9172-9301
Rui LiangDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Gabriel Christopher PurnellThe University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Lei YanDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Alia NazarullahDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Sarah HackmanDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Courtney ThomasDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Aaron M AbarbanellDepartment of Cardiothoracic Surgery, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Aaron SugalskiDepartment of Pediatrics, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Jeffrey L FosterDepartment of Radiology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Linda P ThomasDepartment of Radiology, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Phillip OngDepartment of Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Daniel DeArmondDepartment of Cardiothoracic Surgery, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Marjorie Parker DavidDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA.
Faqian LiDepartment of Pathology and Laboratory Medicine, The University of Texas Health Science Center at San Antonio, San Antonio, Texas, USA lif2@uthscsa.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary lung tumours are rare in paediatric patients. Mucoepidermoid carcinoma (MEC), typically low-grade and diagnostically straightforward, is the second most common tumour of the bronchus after carcinoid tumours. However, rare MEC may show divergent differentiation, be misdiagnosed as low-grade adenocarcinoma, not otherwise classified, and pose clinical challenges, especially when mastermind-like protein 2 (MAML2) gene arrangement is negative by fluorescence in situ hybridisation (FISH). Here, we report an MAML2 FISH-negative low-grade bronchial tumour in a juvenile patient that demonstrates both mucoepidermoid and acinar differentiation based on morphology and immunophenotype. Next-generation sequencing identified a CREB regulated transcription coactivator 3 (

Indexed as

Bronchial NeoplasmsCarcinoma, MucoepidermoidBiomarkers, TumorCell DifferentiationHigh-Throughput Nucleotide SequencingHumansIn Situ Hybridization, FluorescenceTrans-ActivatorsTranscription FactorsBiomarkers, TumorCRTC3 protein, humanMAML2 protein, humanTrans-ActivatorsTranscription FactorsGenes, NeoplasmLung NeoplasmsPediatrics

Identifiers

PMID40829871
PMCPMC12911561

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.