Evidence map›Paper›PMID 40829836›Full record

Observational studyBMJ open2025

Comparing predictive accuracy of carotid artery ultrasonography with inferior vena cava ultrasonography for predicting postinduction hypotension in older patients: a prospective observational study.

Jiafeng Fu, Qing Li, Xiaoping Zhu, Weihong Zhao, Yanfei Lu, Foquan Luo

Abstract readObservational StudyComparative Study
In one paragraph

Observational study in BMJ open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Jiafeng FuCenter for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China.
Qing LiDepartment of Anesthesiology, Nanchang Hongdu Hospital of TCM, Nanchang, Jiangxi, China.
Xiaoping ZhuDepartment of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Weihong ZhaoDepartment of Anesthesiology, The First Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Yanfei LuCenter for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China.
Foquan LuoCenter for Rehabilitation Medicine, Department of Anesthesiology, Zhejiang Provincial People's Hospital (Affiliated People's Hospital, Hangzhou Medical College), Hangzhou, Zhejiang, China lfqxmc@ncu.edu.cn.ORCID http://orcid.org/0009-0005-6906-6328

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesHypotension frequently occurs following the initiation of general anaesthesia, particularly in older individuals, and is linked to adverse postoperative consequences when it is severe. This study was designed to compare the predictive effects of carotid ultrasound measurements and inferior vena cava (IVC) ultrasound measurements on postinduction hypotension (PIH) in older patients.

designProspective observational study.

methodsA total of 102 older adults who were scheduled for elective gastrointestinal surgery were included in the study. Before general anaesthesia induction, maximum IVC diameter (dIVCmax), minimum IVC diameter (dIVCmin), collapsibility index of IVC (IVC-CI), respiratory variation in carotid artery blood flow peak velocity (ΔVpeak) and carotid corrected flow time (FTc) were measured by ultrasound. FTc(B) and FTc(W) were calculated by applying Bazett's formula and Wodey's formula, respectively. Patients were divided into hypotensive and non-hypotension group according to whether the systolic blood pressure (SBP) decreased more than 30% from the baseline or the absolute value of SBP was less than 90 mm Hg within 15 min after anaesthesia induction.

resultsAfter the induction, hypotension was observed in 49% of the patients. The area under the receiver operating characteristics curve (AUROC) of FTc(W), FTc(B) and △Vpeak for predicting PIH were 0.815, 0.691 and 0.713; the optimal cut-off values were 334.7 ms, 348.3 ms and 6.35%, respectively. The AUROC of IVC-CI, dIVCmax and dIVCmin for predicting PIH were 0.666, 0.680 and 0.702; the optimal cut-off values were 46%, 0.985 cm and 0.635 cm, respectively. The AUC of the FTc(W) was significantly higher than that of the FTc(B) (p=0.003), IVC-CI (p=0.024) and dIVCmax (p=0.046).

conclusionsThe FTc(W) values measured by ultrasonography were more accurate for predicting PIH in the older patients as compared with dIVCmax and IVC-CI. Furthermore, the predictive accuracy of FTc(W) is better than FTc(B). TRIAL REGISTRATION NUMBER: ChiCTR2100054532.

Indexed as

Anesthesia, GeneralCarotid ArteriesHypotensionVena Cava, InferiorAgedAged, 80 and overFemaleHumansMalePredictive Value of TestsProspective StudiesROC CurveUltrasonographyUltrasonography, Carotid ArteriesAdult anaesthesiaAgedAgingUltrasound

Identifiers

PMID40829836
PMCPMC12366588

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.